Rhegmatogenous retinal detachments associated to Stickler syndrome in a tertiary eye care center in Saudi Arabia

• Published in: Clinical ophthalmology (Auckland, N.Z.) N.Z.), 2016-01, Vol.10 (Issue 1), p.1-6
• Main Authors: Alshahrani, Saeed T, Ghazi, Nicola G, Al-Rashaed, Saba
• Format: Article
• Language: English
• Subjects: Buckling; Cataracts; Cryotherapy; Detaching; Eye; Eyes; Gulf States; Hospitals; Lasers; Medical research; Medicine, Experimental; Mutation; Original Research; Patients; Retina; retinopexy; rhegmatogenous retinal detachment; Saudi Arabia; Silicones; Stickler syndrome; Studies; Success; Surgery; Visual acuity
• ISSN: 1177-5467; 1177-5483; 1177-5483
• DOI: 10.2147/OPTH.S91444

To investigate the clinical findings and outcomes of rhegmatogenous retinal detachment (RRD) in Stickler syndrome on affected and fellow eyes that underwent prophylactic retinopexy. Chart review of 70 eyes (62 patients). Incidence of RRD, postoperative visual acuity, and risk factors were evaluated. Twenty-two patients (35%) had RRD in the fellow eye, 37% of the eyes had cataract, 93% had macular detachment, 50% had proliferative vitreoretinopathy, and 41% had posterior vitreous detachment. Success rates were: 60% of patients after scleral buckling; 57.1% after pars plana vitrectomy; and 75% after combined scleral buckling and pars plana vitrectomy. Sixty-one (93.8%) of patients had successful surgery (including second surgery). Silicone oil tamponade was significantly associated with final anatomic outcome, with a protective odds ratio of 0.11 (P=0.027). Visual acuity improved in 54% of eyes and decreased in 5%. Statistically significant associations were present for eyes with final visual acuity ≥20/200, and total retinal detachment (P