Pleomorphic sarcoma of the oral cavity: A rare case entity

Pleomorphic sarcomas are extremely rare in the oral cavity, representing only 5% of all soft tissue sarcomas in the extremities of adults. They form a group of highly undifferentiated pleomorphic malignant tumors. A 36-year-old male reported to the OP with a chief complaint of a tooth ache in the ri...

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Bibliographic Details
Published in:Journal of pharmacy & bioallied science 2021-11, Vol.13 (6), p.1747-1749
Main Authors: Rajan, Sharada, Elengkumaran, S, Narasimhan, Malathi, Ravindran, C
Format: Article
Language:English
Subjects:
Biopsy
Case Report
Lesions
mitosis
Oral cavity
pleomorphism
Sarcoma
Teeth
Tumors
undifferentiated pleomorphic sarcoma
undifferentiated tumor
vimentin positivity
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Summary:Pleomorphic sarcomas are extremely rare in the oral cavity, representing only 5% of all soft tissue sarcomas in the extremities of adults. They form a group of highly undifferentiated pleomorphic malignant tumors. A 36-year-old male reported to the OP with a chief complaint of a tooth ache in the right lower quadrant for the past 6 months. The patient gave a history of extraction of a mobile tooth in that region. A radiograph of the region was advised. An incisional biopsy was also done and sent for histopathological examination. The microscopy revealed the presence of spindle-shaped cells showing dysplastic features. A panel of immunohistochemical markers were performed to identify the tissue of origin of the lesion. The article details the clinical, radiographic, and microscopic features of a pleomorphic soft tissue lesion along with the array of immunohistochemical markers, leading to the final diagnosis of such enigmatic lesions.
ISSN:0975-7406
0976-4879
0975-7406
DOI:10.4103/jpbs.jpbs_197_21