Pleomorphic sarcoma of the oral cavity: A rare case entity

Pleomorphic sarcomas are extremely rare in the oral cavity, representing only 5% of all soft tissue sarcomas in the extremities of adults. They form a group of highly undifferentiated pleomorphic malignant tumors. A 36-year-old male reported to the OP with a chief complaint of a tooth ache in the ri...

Full description

Saved in:
Bibliographic Details
Published in:Journal of pharmacy & bioallied science 2021-11, Vol.13 (6), p.1747-1749
Main Authors: Rajan, Sharada, Elengkumaran, S, Narasimhan, Malathi, Ravindran, C
Format: Article
Language:English
Subjects:
Biopsy
Case Report
Lesions
mitosis
Oral cavity
pleomorphism
Sarcoma
Teeth
Tumors
undifferentiated pleomorphic sarcoma
undifferentiated tumor
vimentin positivity
Citations: Items that this one cites
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
cited_by
cites cdi_FETCH-LOGICAL-c495p-f517592a2ccdebc919b23131d8a58c73a1f747dc5af2d8a33b10e3f798b83f053
container_end_page 1749
container_issue 6
container_start_page 1747
container_title Journal of pharmacy & bioallied science
container_volume 13
creator Rajan, Sharada
Elengkumaran, S
Narasimhan, Malathi
Ravindran, C
description Pleomorphic sarcomas are extremely rare in the oral cavity, representing only 5% of all soft tissue sarcomas in the extremities of adults. They form a group of highly undifferentiated pleomorphic malignant tumors. A 36-year-old male reported to the OP with a chief complaint of a tooth ache in the right lower quadrant for the past 6 months. The patient gave a history of extraction of a mobile tooth in that region. A radiograph of the region was advised. An incisional biopsy was also done and sent for histopathological examination. The microscopy revealed the presence of spindle-shaped cells showing dysplastic features. A panel of immunohistochemical markers were performed to identify the tissue of origin of the lesion. The article details the clinical, radiographic, and microscopic features of a pleomorphic soft tissue lesion along with the array of immunohistochemical markers, leading to the final diagnosis of such enigmatic lesions.
doi_str_mv 10.4103/jpbs.jpbs_197_21
format article
fullrecord <record><control><sourceid>gale_doaj_</sourceid><recordid>TN_cdi_doaj_primary_oai_doaj_org_article_3f431ff00649414a992d2d756577f8af</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A682462262</galeid><doaj_id>oai_doaj_org_article_3f431ff00649414a992d2d756577f8af</doaj_id><sourcerecordid>A682462262</sourcerecordid><originalsourceid>FETCH-LOGICAL-c495p-f517592a2ccdebc919b23131d8a58c73a1f747dc5af2d8a33b10e3f798b83f053</originalsourceid><addsrcrecordid>eNp1Uk1rGzEUFKWlCWnuPZWFnu3qW6scCsakbSCQHtqz0GolW87uaiutY_Lv-xInqQ2NHujjaWbQoEHoI8FzTjD7shmbMn-YDNHKUPIGnWKtxExxLN8e7E_QeSkbDINpqgl7j06YwKTGUp-ii5-dT33K4zq6qtjsUm-rFKpp7auUbVc5exen-4tqUWWbPRyLr_wwQe8DehdsV_z503qGfn-7_LX8Mbu--X61XFzPHNdinAVBlNDUUuda3zhNdEMZYaStraidYpYExVXrhA0Ueow1BHsWlK6bmgUs2Bm62uu2yW7MmGNv871JNprHRsorY_MUXecNC5yREDCWXHPCrda0pa0SUigVahtA6-tea9w2vW8dOAGTR6LHN0Ncm1W6M7WEUgoEPj8J5PRn68tkNmmbB_BvqNCKMyaZ_odaWXhVHEICMdfH4sxC1pRLSiUF1Pw_KKjW99GlwYcI_SMC3hNcTqVkH14eTrB5yIR5jMNBJoDy6dDwC-E5AQBY7gG71E0-l9tuu_PZAPZ2SLtXhQ2BTzPP4WF_AScCycs</addsrcrecordid><sourcetype>Open Website</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2597433639</pqid></control><display><type>article</type><title>Pleomorphic sarcoma of the oral cavity: A rare case entity</title><source>Publicly Available Content Database</source><source>PubMed Central</source><creator>Rajan, Sharada ; Elengkumaran, S ; Narasimhan, Malathi ; Ravindran, C</creator><creatorcontrib>Rajan, Sharada ; Elengkumaran, S ; Narasimhan, Malathi ; Ravindran, C</creatorcontrib><description>Pleomorphic sarcomas are extremely rare in the oral cavity, representing only 5% of all soft tissue sarcomas in the extremities of adults. They form a group of highly undifferentiated pleomorphic malignant tumors. A 36-year-old male reported to the OP with a chief complaint of a tooth ache in the right lower quadrant for the past 6 months. The patient gave a history of extraction of a mobile tooth in that region. A radiograph of the region was advised. An incisional biopsy was also done and sent for histopathological examination. The microscopy revealed the presence of spindle-shaped cells showing dysplastic features. A panel of immunohistochemical markers were performed to identify the tissue of origin of the lesion. The article details the clinical, radiographic, and microscopic features of a pleomorphic soft tissue lesion along with the array of immunohistochemical markers, leading to the final diagnosis of such enigmatic lesions.</description><identifier>ISSN: 0975-7406</identifier><identifier>ISSN: 0976-4879</identifier><identifier>EISSN: 0975-7406</identifier><identifier>DOI: 10.4103/jpbs.jpbs_197_21</identifier><identifier>PMID: 35018069</identifier><language>eng</language><publisher>India: Wolters Kluwer India Pvt. Ltd</publisher><subject>Biopsy ; Case Report ; Lesions ; mitosis ; Oral cavity ; pleomorphism ; Sarcoma ; Teeth ; Tumors ; undifferentiated pleomorphic sarcoma ; undifferentiated tumor ; vimentin positivity</subject><ispartof>Journal of pharmacy &amp; bioallied science, 2021-11, Vol.13 (6), p.1747-1749</ispartof><rights>Copyright: © 2021 Journal of Pharmacy and Bioallied Sciences.</rights><rights>COPYRIGHT 2021 Medknow Publications and Media Pvt. Ltd.</rights><rights>2021. This article is published under (http://creativecommons.org/licenses/by-nc-sa/3.0/) (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>Copyright: © 2021 Journal of Pharmacy and Bioallied Sciences 2021</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c495p-f517592a2ccdebc919b23131d8a58c73a1f747dc5af2d8a33b10e3f798b83f053</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC8686877/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.proquest.com/docview/2597433639?pq-origsite=primo$$EHTML$$P50$$Gproquest$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,25753,27924,27925,37012,44590,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/35018069$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Rajan, Sharada</creatorcontrib><creatorcontrib>Elengkumaran, S</creatorcontrib><creatorcontrib>Narasimhan, Malathi</creatorcontrib><creatorcontrib>Ravindran, C</creatorcontrib><title>Pleomorphic sarcoma of the oral cavity: A rare case entity</title><title>Journal of pharmacy &amp; bioallied science</title><addtitle>J Pharm Bioallied Sci</addtitle><description>Pleomorphic sarcomas are extremely rare in the oral cavity, representing only 5% of all soft tissue sarcomas in the extremities of adults. They form a group of highly undifferentiated pleomorphic malignant tumors. A 36-year-old male reported to the OP with a chief complaint of a tooth ache in the right lower quadrant for the past 6 months. The patient gave a history of extraction of a mobile tooth in that region. A radiograph of the region was advised. An incisional biopsy was also done and sent for histopathological examination. The microscopy revealed the presence of spindle-shaped cells showing dysplastic features. A panel of immunohistochemical markers were performed to identify the tissue of origin of the lesion. The article details the clinical, radiographic, and microscopic features of a pleomorphic soft tissue lesion along with the array of immunohistochemical markers, leading to the final diagnosis of such enigmatic lesions.</description><subject>Biopsy</subject><subject>Case Report</subject><subject>Lesions</subject><subject>mitosis</subject><subject>Oral cavity</subject><subject>pleomorphism</subject><subject>Sarcoma</subject><subject>Teeth</subject><subject>Tumors</subject><subject>undifferentiated pleomorphic sarcoma</subject><subject>undifferentiated tumor</subject><subject>vimentin positivity</subject><issn>0975-7406</issn><issn>0976-4879</issn><issn>0975-7406</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><sourceid>PIMPY</sourceid><sourceid>DOA</sourceid><recordid>eNp1Uk1rGzEUFKWlCWnuPZWFnu3qW6scCsakbSCQHtqz0GolW87uaiutY_Lv-xInqQ2NHujjaWbQoEHoI8FzTjD7shmbMn-YDNHKUPIGnWKtxExxLN8e7E_QeSkbDINpqgl7j06YwKTGUp-ii5-dT33K4zq6qtjsUm-rFKpp7auUbVc5exen-4tqUWWbPRyLr_wwQe8DehdsV_z503qGfn-7_LX8Mbu--X61XFzPHNdinAVBlNDUUuda3zhNdEMZYaStraidYpYExVXrhA0Ueow1BHsWlK6bmgUs2Bm62uu2yW7MmGNv871JNprHRsorY_MUXecNC5yREDCWXHPCrda0pa0SUigVahtA6-tea9w2vW8dOAGTR6LHN0Ncm1W6M7WEUgoEPj8J5PRn68tkNmmbB_BvqNCKMyaZ_odaWXhVHEICMdfH4sxC1pRLSiUF1Pw_KKjW99GlwYcI_SMC3hNcTqVkH14eTrB5yIR5jMNBJoDy6dDwC-E5AQBY7gG71E0-l9tuu_PZAPZ2SLtXhQ2BTzPP4WF_AScCycs</recordid><startdate>20211101</startdate><enddate>20211101</enddate><creator>Rajan, Sharada</creator><creator>Elengkumaran, S</creator><creator>Narasimhan, Malathi</creator><creator>Ravindran, C</creator><general>Wolters Kluwer India Pvt. Ltd</general><general>Medknow Publications and Media Pvt. Ltd</general><general>Medknow Publications &amp; Media Pvt. Ltd</general><general>Wolters Kluwer - Medknow</general><general>Wolters Kluwer Medknow Publications</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB0</scope><scope>LK8</scope><scope>M0S</scope><scope>M2O</scope><scope>M7P</scope><scope>MBDVC</scope><scope>NAPCQ</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>Q9U</scope><scope>5PM</scope><scope>DOA</scope></search><sort><creationdate>20211101</creationdate><title>Pleomorphic sarcoma of the oral cavity: A rare case entity</title><author>Rajan, Sharada ; Elengkumaran, S ; Narasimhan, Malathi ; Ravindran, C</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c495p-f517592a2ccdebc919b23131d8a58c73a1f747dc5af2d8a33b10e3f798b83f053</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>Biopsy</topic><topic>Case Report</topic><topic>Lesions</topic><topic>mitosis</topic><topic>Oral cavity</topic><topic>pleomorphism</topic><topic>Sarcoma</topic><topic>Teeth</topic><topic>Tumors</topic><topic>undifferentiated pleomorphic sarcoma</topic><topic>undifferentiated tumor</topic><topic>vimentin positivity</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Rajan, Sharada</creatorcontrib><creatorcontrib>Elengkumaran, S</creatorcontrib><creatorcontrib>Narasimhan, Malathi</creatorcontrib><creatorcontrib>Ravindran, C</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Nursing &amp; Allied Health Database</collection><collection>Health &amp; Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep (ProQuest)</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health &amp; Medical Complete (Alumni)</collection><collection>Nursing &amp; Allied Health Database (Alumni Edition)</collection><collection>ProQuest Biological Science Collection</collection><collection>Health &amp; Medical Collection (Alumni Edition)</collection><collection>ProQuest research library</collection><collection>Biological Science Database</collection><collection>Research Library (Corporate)</collection><collection>Nursing &amp; Allied Health Premium</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest Central Basic</collection><collection>PubMed Central (Full Participant titles)</collection><collection>Directory of Open Access Journals</collection><jtitle>Journal of pharmacy &amp; bioallied science</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Rajan, Sharada</au><au>Elengkumaran, S</au><au>Narasimhan, Malathi</au><au>Ravindran, C</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Pleomorphic sarcoma of the oral cavity: A rare case entity</atitle><jtitle>Journal of pharmacy &amp; bioallied science</jtitle><addtitle>J Pharm Bioallied Sci</addtitle><date>2021-11-01</date><risdate>2021</risdate><volume>13</volume><issue>6</issue><spage>1747</spage><epage>1749</epage><pages>1747-1749</pages><issn>0975-7406</issn><issn>0976-4879</issn><eissn>0975-7406</eissn><abstract>Pleomorphic sarcomas are extremely rare in the oral cavity, representing only 5% of all soft tissue sarcomas in the extremities of adults. They form a group of highly undifferentiated pleomorphic malignant tumors. A 36-year-old male reported to the OP with a chief complaint of a tooth ache in the right lower quadrant for the past 6 months. The patient gave a history of extraction of a mobile tooth in that region. A radiograph of the region was advised. An incisional biopsy was also done and sent for histopathological examination. The microscopy revealed the presence of spindle-shaped cells showing dysplastic features. A panel of immunohistochemical markers were performed to identify the tissue of origin of the lesion. The article details the clinical, radiographic, and microscopic features of a pleomorphic soft tissue lesion along with the array of immunohistochemical markers, leading to the final diagnosis of such enigmatic lesions.</abstract><cop>India</cop><pub>Wolters Kluwer India Pvt. Ltd</pub><pmid>35018069</pmid><doi>10.4103/jpbs.jpbs_197_21</doi><tpages>3</tpages><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 0975-7406
ispartof Journal of pharmacy & bioallied science, 2021-11, Vol.13 (6), p.1747-1749
issn 0975-7406
0976-4879
0975-7406
language eng
recordid cdi_doaj_primary_oai_doaj_org_article_3f431ff00649414a992d2d756577f8af
source Publicly Available Content Database; PubMed Central
subjects Biopsy
Case Report
Lesions
mitosis
Oral cavity
pleomorphism
Sarcoma
Teeth
Tumors
undifferentiated pleomorphic sarcoma
undifferentiated tumor
vimentin positivity
title Pleomorphic sarcoma of the oral cavity: A rare case entity
url http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-01T20%3A27%3A59IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-gale_doaj_&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Pleomorphic%20sarcoma%20of%20the%20oral%20cavity:%20A%20rare%20case%20entity&rft.jtitle=Journal%20of%20pharmacy%20&%20bioallied%20science&rft.au=Rajan,%20Sharada&rft.date=2021-11-01&rft.volume=13&rft.issue=6&rft.spage=1747&rft.epage=1749&rft.pages=1747-1749&rft.issn=0975-7406&rft.eissn=0975-7406&rft_id=info:doi/10.4103/jpbs.jpbs_197_21&rft_dat=%3Cgale_doaj_%3EA682462262%3C/gale_doaj_%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c495p-f517592a2ccdebc919b23131d8a58c73a1f747dc5af2d8a33b10e3f798b83f053%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=2597433639&rft_id=info:pmid/35018069&rft_galeid=A682462262&rfr_iscdi=true