The histopathological changes of liver and testis of Japanese quail chicks fed different levels of dietary L-valine

• Published in: Veterinary and animal science 2023-09, Vol.21, p.100302-100302, Article 100302
• Main Authors: Rashidi, Ali, Alizadeh, AliReza, Sharifi, Seyed Davood, Najafi, Abouzar
• Format: Article
• Language: English
• Subjects: Histological response; L-Valine; Liver; Quail; Testis
• ISSN: 2451-943X; 2451-943X
• DOI: 10.1016/j.vas.2023.100302

•The diameter of liver cell nuclei and liver hepatocytes increased with increasing dietary valine intake in both male and female quails.•Male quails fed 8.5 g of valine per kg of diet showed better tubular differentiation and spermatic indexes compared to those fed valine at levels greater than 8.5 g/kg.•High levels of dietary valine led to bile duct hyperplasia and hepatosteatosis in quails.•Feeding high levels of valine led to histological damage in the liver and testes of quails. This experiment was carried out to investigate the histological changes of liver and testis of Japanese quail fed different levels of dietary valine (Val) in low protein diet. A total of 1000 one-day-old Japanese quail chicks (mixed sex) were assigned to five experimental diets including diets containing 7.5, 8.5, 9.5, 10.5 and 11.5 g digestible (dig.) Val/kg diet in a completely randomized design, with 5 replicates of 40 quail chicks per pen. Experimental diets were formulated to be isoenergetic and isonitrogenous (170 g crude protein/kg) to meet nutrients recommendation of growing quails suggested by Brazilian tables. At d 42, quail chicks were slaughtered, and tissue samples were collected and fixed to evaluate the histological indices of liver and testis. High levels of Val, increased (P