Coexistence of squamous cell tracheal papilloma and carcinoma treated with chemotherapy and radiotherapy: a case report

Papillomatosis presents, most frequently, as multiple lesions of the respiratory tract, which are usually considered benign. Malignant degeneration into squamous cell carcinoma is quite common, although curative approaches vary a lot in modern literature. We report a case of a 66-year-old male patie...

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Bibliographic Details
Published in:Therapeutics and clinical risk management 2016-01, Vol.12 (Issue 1), p.1-4
Main Authors: Paliouras, Dimitrios, Gogakos, Apostolos, Rallis, Thomas, Chatzinikolaou, Fotios, Asteriou, Christos, Tagarakis, Georgios, Organtzis, John, Tsakiridis, Kosmas, Tsavlis, Drosos, Zissimopoulos, Athanasios, Kioumis, Ioannis, Hohenforst-Schmidt, Wolfgang, Zarogoulidis, Konstantinos, Zarogoulidis, Paul, Barbetakis, Nikolaos
Format: Article
Language:English
Subjects:
Airway management
Cancer
Case Report
Case reports
Chemotherapy
Drug dosages
Dyspnea
Hospitals
Human papillomavirus
Larynx
Medical prognosis
Oncology
Ostomy
papilloma
Patients
Radiation therapy
Squamous cell carcinoma
Surgery
trachea
Tumors
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Summary:Papillomatosis presents, most frequently, as multiple lesions of the respiratory tract, which are usually considered benign. Malignant degeneration into squamous cell carcinoma is quite common, although curative approaches vary a lot in modern literature. We report a case of a 66-year-old male patient with the coexistence of multiple squamous cell papilloma and carcinoma in the upper trachea with severe airway obstruction that was diagnosed through bronchoscopy and treated by performing an urgent tracheostomy, followed by concurrent chemotherapy and radiotherapy. There was no evidence of recurrence after a 12-month follow-up period. This study underlines the diagnostic and therapeutic value of bronchoscopy as well as multimodality palliative treatment in such cases. To the best of our knowledge, this is the first study to describe an immediate treatment protocol with tracheostomy and concurrent chemotherapy/radiotherapy in a patient with squamous cell tracheal papilloma and carcinoma.
ISSN:1176-6336
1178-203X
1178-203X
DOI:10.2147/TCRM.S95233