The value of NIPT combined with serum cell-free DNA, estriol, AFP, and b-HCG levels in the recognition of trisomy 21 and 18 in the second trimester

This study aimed to evaluate the clinical application value of noninvasive prenatal testing from DNA (NIPT) and serum screening for screening in detecting fetal trisomy 21 and 18. As a retrospective analysis, we collected data from 1383 women (singleton pregnancy) who underwent serum screening and n...

Full description

Saved in:
Bibliographic Details
Published in:Journal of medical biochemistry 2023-10, Vol.42 (4), p.574-581
Main Authors: Fu, JingLi, Zhong, XiaoYan, Li, Dan, Ge, YunSheng, Zhang, XueQin
Format: Article
Language:English
Subjects:
noninvasive prenatal testing from dna (nipt)
Original Paper
serum screening
trisomy syndrome
Citations: Items that this one cites
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:This study aimed to evaluate the clinical application value of noninvasive prenatal testing from DNA (NIPT) and serum screening for screening in detecting fetal trisomy 21 and 18. As a retrospective analysis, we collected data from 1383 women (singleton pregnancy) who underwent serum screening and noninvasive prenatal testing from DNA (NIPT) in our department from May 2015 to September 2017 and calculated the diagnostic value of the two methods.
ISSN:1452-8258
1452-8266
DOI:10.5937/jomb0-33027