Contact Allergy to Oxidized Linalool and Oxidized Limonene is Over-represented in Individuals with Photocontact Allergy to Ketoprofen

Simultaneous contact allergies are common in individuals with photocontact allergy to ketoprofen. The rate of contact allergy to the fragrance substances oxidized linalool and oxidized limonene in ketoprofen-photo-allergic individuals were investigated in comparison with the corresponding rates in i...

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Bibliographic Details
Published in:Acta dermato-venereologica 2021-05, Vol.101 (5), p.adv00454-adv00454
Main Authors: Bruze, Magnus, Marmgren, Victoria, Antelmi, Annarita, Hindsén Stenström, Monica, Svedman, Cecilia, Zimersson, Erik, Mowitz, Martin
Format: Article
Language:English
Subjects:
allergic contact dermatitis
Clinical Medicine
delayed hypersensitivity
delayedhypersensitivity
Dermatologi och venereologi
Dermatology and Venereal Diseases
fragrance substance
Investigative Report
Klinisk medicin
Medical and Health Sciences
Medicin och hälsovetenskap
oxidation
patch- testing
photoallergic
photopatch-testing
photosensitizer
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Summary:Simultaneous contact allergies are common in individuals with photocontact allergy to ketoprofen. The rate of contact allergy to the fragrance substances oxidized linalool and oxidized limonene in ketoprofen-photo-allergic individuals were investigated in comparison with the corresponding rates in individuals without photo-contact allergy to ketoprofen, using Fisher's exact test. A total of 4,021 patients were routinely tested with oxidized linalool; of whom 190 (4.7%) tested positively. For oxidized limonene the numbers were 3,797 patients and 111 positive reactions (2.9%). A total of 19 contact allergic reactions to oxidized linalool were noted in 29 patients (65.5%) who also had photocontact allergy to ketoprofen (p 
ISSN:1651-2057
0001-5555
1651-2057
DOI:10.2340/00015555-3799