Resolution of macular edema in Coats' disease with intravitreal bevacizumab

A 13-year-old boy was referred because of visual deterioration in his right eye. The visual acuity was two meters of counting fingers. Indirect ophthalmoscopy and biomicroscopy revealed exudative macular edema as well as tumor-like telangiectatic vessels and exudation in temporal periphery. With dia...

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Bibliographic Details
Published in:Indian journal of ophthalmology 2010-01, Vol.58 (1), p.80-82
Main Authors: Entezari, Morteza, Ramezani, Alireza, Safavizadeh, Ladan, Bassirnia, Nader
Format: Article
Language:English
Subjects:
Adolescent
Angiogenesis Inhibitors - administration & dosage
Antibodies, Monoclonal - administration & dosage
Antibodies, Monoclonal, Humanized
Bevacizumab
Brief Communications
Case studies
Clinical trials
coats′ disease
Complications and side effects
Diagnosis
Diagnosis, Differential
Drug therapy
Eye diseases
Follow-Up Studies
Humans
Injections
macular edema
Macular Edema - complications
Macular Edema - diagnosis
Macular Edema - drug therapy
Male
Medical research
Microscopy, Acoustic
Ophthalmoscopy
Retinal Diseases - complications
Retinal Diseases - diagnosis
Retinal Diseases - drug therapy
Retinal Vessels - pathology
Risk factors
Telangiectasis - complications
Telangiectasis - diagnosis
Telangiectasis - drug therapy
Vascular Endothelial Growth Factor A - antagonists & inhibitors
Visual Acuity
Vitreous Body
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Summary:A 13-year-old boy was referred because of visual deterioration in his right eye. The visual acuity was two meters of counting fingers. Indirect ophthalmoscopy and biomicroscopy revealed exudative macular edema as well as tumor-like telangiectatic vessels and exudation in temporal periphery. With diagnosis of Coats' disease (stage II) confirmed by fluorescein angiography, three intravitreal injections of bevacizumab were performed at 6-week intervals. One year after the last injection, there was a significant resolution of macular edema as well as visual acuity improvement to 20/20. This is the first case report in which a distinct improvement in macular edema was observed with intravitreal bevacizumab in Coats' disease.
ISSN:0301-4738
1998-3689
DOI:10.4103/0301-4738.58482