Association of urogenital and intestinal parasitic infections with type 2 diabetes individuals: a comparative study

• Published in: BMC infectious diseases 2021-01, Vol.21 (1), p.20-20, Article 20
• Main Authors: Almugadam, Babiker Saad, Ibrahim, Mihad Khaleil, Liu, Yinhui, Chen, Shen-Min, Wang, Chun-Hao, Shao, Chen-Yi, Ren, Bao-Wei, Tang, Li
• Format: Article
• Language: English
• Subjects: Adult; Age; Aged; Aged, 80 and over; Case-Control Studies; Comparative studies; Complications and side effects; Demographic aspects; Diabetes; Diabetes mellitus; Diabetes mellitus (non-insulin dependent); Diabetes Mellitus, Type 2 - complications; Diabetes Mellitus, Type 2 - parasitology; Diagnosis; Eggs; Feces; Feces - parasitology; Female; Helminthiasis; Helminthiasis - epidemiology; Humans; Independent sample; Infections; Infectious diseases; Intestinal Diseases, Parasitic - epidemiology; Intestinal Diseases, Parasitic - parasitology; Intestinal parasites; Intestinal parasitic infections; Intestine; Male; Middle Aged; Morbidity; Mortality; Parasites; Parasitic diseases; Parasitosis; Prevalence; Questionnaires; Risk factors; Rural Population; Schistosomiasis; Schistosomiasis haematobia - epidemiology; Sedimentation; Sociodemographics; Sudan - epidemiology; Teaching hospitals; Teaching methods; Type 2 diabetes; Type 2 diabetes mellitus; Urine; Young Adult
• ISSN: 1471-2334; 1471-2334
• DOI: 10.1186/s12879-020-05629-9

Globally, urogenital and intestinal parasitosis remain significant health challenges. They are associated with rising morbidity, death, and many harmful outcomes. A little is known concerning parasitosis and type 2 diabetes mellitus. Our study planned to investigate the urogenital and intestinal parasitic infections among type 2 diabetes patients compare to non-diabetic (Control) individuals and examine the intensity of helminthiasis in both groups. At Kosti Teaching Hospital (Sudan), 300 Urine and 300 stool samples have collected from 150 type 2 diabetes and 150 control individuals, along with the socio-demographic data using a structured questionnaire. The parasitic infections were examined by direct sedimentation technique for urine specimens. Whereas, for fecal samples, simple-direct saline, formal-ether concentration, Kato-Katz, and modified Ziehl-Neelsen techniques were used. Out of 150 type 2 diabetes patients studied, 31 (20.6%) and 14 (9.3%) had intestinal parasitosis and urogenital schistosomiasis, respectively. Whereas, 16 (10.6%) and 8 (5.3%) of the control group were infected, respectively. Compared to the control group, the odds of testing positive for either urogenital schistosomiasis (AOR: 2.548, 95% CI: 0.836-7.761, P = 0.100) or intestinal parasitic diseases (AOR: 2.099, 95% CI: 0.973-4.531, P = 0.059) were greater in diabetic individuals. Likewise, the intensities of helminthiasis were much higher in the diabetic patients and positively correlated with the duration of illness. The rate of urogenital schistosomiasis was also significantly different among the disease duration subcategories. Our study has highlighted the relationship of type 2 diabetes with urogenital and intestinal parasitic infections and enhanced our knowledge about the frequency of particular urogenital and intestinal parasites as well as the intensity of helminths infection in type 2 diabetes compared to non-diabetic individuals, which are important for further studies.