Asymptomatic HIV positive patient presenting with myelopathy

A wide variety of disorders of diverse pathogenic mechanisms can trigger spinal cord dysfunction in HIV-1-infected patients. The most common such condition is HIV-1-associated myelopathy (HAM) which characteristically seen during advanced HIV infection in patients with low CD4 cell counts and previo...

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Bibliographic Details
Published in:International Journal of Advanced Medical and Health Research 2016-01, Vol.3 (1), p.25-27
Main Authors: Agrawal, Jatin, Singh, Veer, Kumar, Harish, Meena, Babu, Chandra, Subhash, Kumar, Rajesh
Format: Article
Language:English
Subjects:
Anti-retroviral therapy
CD count
Health aspects
HIV
HIV infections
HIV patients
Infection
myelopathy
spinal cord
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Summary:A wide variety of disorders of diverse pathogenic mechanisms can trigger spinal cord dysfunction in HIV-1-infected patients. The most common such condition is HIV-1-associated myelopathy (HAM) which characteristically seen during advanced HIV infection in patients with low CD4 cell counts and previous AIDS-defining diagnoses. Histologically seen in approximately 30% of AIDS patients, but only 10% have clinical symptoms related to the disease. We describe an unusual case of HAM in previously asymptomatic patient with relatively low CD4 cell count (78 cells/mm3). The patient unaware of her seropositive status presented with a clinically slowly progressive myelopathy with difficulty in walking without assistance. We discharged a patient on antiretroviral therapy. We also review the disorders reported to derange spinal cord function in previously asymptomatic HIV-1 infected patients with preserved counts.
ISSN:2349-4220
2350-0298
DOI:10.4103/2350-0298.184682