Unilateral hypopyon in a child as a first and sole presentation in relapsing acute lymphoblastic leukemia

Ocular manifestations form a part of the spectrum of varied clinical presentations in leukemias. Most of the ophthalmic manifestations are related to central nervous system leukemia and bone marrow relapse. We report a case of acute unilateral hypopyon uveitis as an initial presenting feature of rel...

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Bibliographic Details
Published in:Indian journal of ophthalmology 2007-05, Vol.55 (3), p.223-224
Main Authors: Wadhwa, Neeraj, Vohra, Rajpal, Shrey, Dinesh, Iyer, V K, Garg, Satpal
Format: Article
Language:English
Subjects:
Acute lymphoblastic leukemia
Acute lymphocytic leukemia
Anterior Chamber
Cancer
Cancer in children
Case studies
Child, Preschool
Complications and side effects
Humans
hypopyon
Male
Ocular manifestations of general diseases
Paracentesis
Precursor Cell Lymphoblastic Leukemia-Lymphoma - complications
Precursor Cell Lymphoblastic Leukemia-Lymphoma - diagnosis
Precursor Cell Lymphoblastic Leukemia-Lymphoma - pathology
Recurrence
Relapse
Risk factors
Suppuration - diagnosis
Suppuration - pathology
Uveitis
Uveitis - etiology
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Summary:Ocular manifestations form a part of the spectrum of varied clinical presentations in leukemias. Most of the ophthalmic manifestations are related to central nervous system leukemia and bone marrow relapse. We report a case of acute unilateral hypopyon uveitis as an initial presenting feature of relapsing acute lymphoblastic leukemia (ALL) in a pediatric patient. Anterior chamber paracentesis was performed in a four-year-old male child presenting with unilateral treatment-resistant hypopyon after remission of ALL. Examination of aqueous humor aspirate revealed presence of malignant cells. Atypical hypopyon, even unilateral can be an indication of relapsing ALL in a child.
ISSN:0301-4738
DOI:10.4103/0301-4738.31947