MRI manifestions correlate with survival of glioblastoma multiforme patients

• Published in: Cancer biology & medicine 2012-06, Vol.9 (2), p.120-123
• Main Authors: Li, Wen-Bin, Tang, Kai, Chen, Qian, Li, Shuai, Qiu, Xiao-Guang, Li, Shao-Wu, Jiang, Tao
• Format: Article
• Language: English
• Subjects: diffusion magnetic resonance imaging; glioblastoma multiforme; Original; survival
• ISSN: 2095-3941; 2095-3941
• DOI: 10.3969/j.issn.2095-3941.2012.02.007

To identify the correlation between magnetic resonance manifestation and survival of patients with glioblastoma multiforme (GBM). The magnetic resonance imaging (MRI) images of 30 glioblastoma patients were collected. Imaging features including degrees of contrasted area, edema surrounding the tumor, and intensity in T2-weighted imaging were selected to determine their correlation with patient survival. The relationship between imaging and survival time was studied using SPSS 19.0 software. Kaplan-Meier survival analysis and log-rank test were used to compare the survival curves. Patients with ≤5% contrasted enhancement area of tumor had longer overall survival (OS) than those with >5% contrasted enhancement area of tumor. Patients without edema surrounding the tumor had longer OS than those with edema. Patients with tumor of hyperintensity and/or isointensity in T2-weighted imaging had longer OS than those with hyperintensity and/or isointensity and hypointensity. Some MR imaging features including degrees of contrasted area, edema surrounding the tumor, and intensity in T2-weighted imaging are correlated with the survival of patients with GBM. These features can serve as prognostic indicators for GBM patients.