Isoniazid-resistant Mycobacterium kansasii in an HIV-positive patient, and possible development of immune reconstitution inflammatory syndrome after initiation of highly active antiretroviral therapy: case report

Highlights • We present the first report of Mycobacterium kansasii pulmonary infection in Serbia. • The course of illness, along with treatment, is documented. • Immune reconstitution inflammatory syndrome (IRIS) is well described in HIV patients treated for mycobacterial infections. • Multidrug-res...

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Bibliographic Details
Published in:International journal of infectious diseases 2016-01, Vol.42 (C), p.40-42
Main Authors: Despotovic, A, Savic, B, Salemovic, D, Ranin, J, Jevtovic, Dj
Format: Article
Language:English
Subjects:
Adult
Antiretroviral Therapy, Highly Active - adverse effects
Antitubercular Agents - pharmacology
HIV Seropositivity - microbiology
Humans
Immune Reconstitution Inflammatory Syndrome - etiology
Infectious Disease
IRIS
Isoniazid - pharmacology
Male
Mycobacterial resistance
Mycobacterium kansasii
Mycobacterium kansasii - drug effects
Mycobacterium kansasii - isolation & purification
NTM
Pulmonary/Respiratory
Serbia
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Summary:Highlights • We present the first report of Mycobacterium kansasii pulmonary infection in Serbia. • The course of illness, along with treatment, is documented. • Immune reconstitution inflammatory syndrome (IRIS) is well described in HIV patients treated for mycobacterial infections. • Multidrug-resistant mycobacteria are an increasing problem. • Several treatment challenges were encountered and are the topic of discussion.
ISSN:1201-9712
1878-3511
DOI:10.1016/j.ijid.2015.11.012