Cognitive dysfunction in patients of rheumatoid arthritis

Rheumatoid Arthritis (RA) is a form of arthritis characterized by joint pain, stiffness, swelling and deformity. There has been plethora of researches in the area of rheumatoid arthritis which focused on immune system, genetic predisposition and newer treatment modalities. Researchers have also exam...

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Bibliographic Details
Published in:Journal of family medicine and primary care 2020-05, Vol.9 (5), p.2219-2225
Main Authors: Chaurasia, Neha, Singh, Anup, Singh, Indramani, Singh, Tara, Tiwari, Trayambak
Format: Article
Language:English
Subjects:
Antiarthritic agents
Arthralgia
Arthritis
attentional functioning
Cognitive disorders
cognitive impairment
Depression (Mood disorder)
Diseases
Fatigue
Immune system
Morbidity
pain
Psychological aspects
Review
rheumatoid arthritis
Rheumatoid factor
Stress (Psychology)
Therapeutics
yoga
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Summary:Rheumatoid Arthritis (RA) is a form of arthritis characterized by joint pain, stiffness, swelling and deformity. There has been plethora of researches in the area of rheumatoid arthritis which focused on immune system, genetic predisposition and newer treatment modalities. Researchers have also examined the cognitive decline, physical deficits and their interrelationship in patients with RA. Among several psychological aspects depression, anxiety and stress emerge as significant psychological co morbidity. RA is a multifactorial, chronic, inflammatory disease primarily affects physical functioning as well as psychological aspects. Pain, fatigue, duration of disease, disease activity and functional disability are very common in rheumatoid arthritis which is leading cause of psychological distress and functional disability. Various types of neuropsychological battery were used to assess the decline in specific areas like attention, executive functioning, visuo-spatial learning, verbal learning/memory etc. These functions were compared with other type of arthritis disease. Also, various other factors like depression, cardiovascular diseases, other systemic and chronic disease and concomitant drugs intake etc. also affected cognitive functioning in Rheumatoid Arthritis patients. The objective of this review was to identify and explore the rates and types of cognitive impairment in RA.This present review paper systematically examines and summarizes the cognition related decrement in arthritis patients. Multiple research articles between 1990 to 2018 were searched. These reviews were evaluated and synthesized using a narrative and descriptive approach.
ISSN:2249-4863
2278-7135
DOI:10.4103/jfmpc.jfmpc_307_20