Analysis of Yarrowia lipolytica growth, catabolism, and terpenoid biosynthesis during utilization of lipid-derived feedstock

This study employs biomass growth analyses and 13C-isotope tracing to investigate lipid feedstock utilization by Yarrowia lipolytica. Compared to glucose, oil-feedstock in the minimal medium increases the yeast's biomass yields and cell sizes, but decreases its protein content (

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Bibliographic Details
Published in:Metabolic engineering communications 2020-12, Vol.11, p.e00130, Article e00130
Main Authors: Worland, Alyssa M., Czajka, Jeffrey J., Xing, Yun, Harper, Willie F., Moore, Aryiana, Xiao, Zhengyang, Han, Zhenlin, Wang, Yechun, Su, Wei Wen, Tang, Yinjie J.
Format: Article
Language:English
Subjects:
13C-isotope tracing
Catabolite repression
Dimorphism
Full Length
Metabolic network
β-carotene
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Description
Summary:This study employs biomass growth analyses and 13C-isotope tracing to investigate lipid feedstock utilization by Yarrowia lipolytica. Compared to glucose, oil-feedstock in the minimal medium increases the yeast's biomass yields and cell sizes, but decreases its protein content (
ISSN:2214-0301
2214-0301
DOI:10.1016/j.mec.2020.e00130