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Edoxaban in elderly patient with morbid obesity and atrial fibrillation: the role of plasma levels evaluation for selecting the appropriate dose
We present the case of a 80-year-old man with atrial fibrillation, morbid obesity (weight 123 kg, height 167 cm, BMI 44.1), high clearance of creatinine and pharmacological polytherapy, in which the serial determinations of edoxaban plasma levels help us to choose the appropriate dose.
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Published in: | Monaldi archives for chest disease 2020-03, Vol.90 (1) |
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container_title | Monaldi archives for chest disease |
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creator | Russo, Vincenzo Rago, Anna Laezza, Nunzia Di Micco, Pierpaolo Giannetti, Laura Atripaldi, Luigi D'Onofrio, Antonio Golino, Paolo Nigro, Gerardo |
description | We present the case of a 80-year-old man with atrial fibrillation, morbid obesity (weight 123 kg, height 167 cm, BMI 44.1), high clearance of creatinine and pharmacological polytherapy, in which the serial determinations of edoxaban plasma levels help us to choose the appropriate dose. |
doi_str_mv | 10.4081/monaldi.2020.1224 |
format | article |
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subjects | Aged, 80 and over Anticoagulants - administration & dosage Anticoagulants - pharmacokinetics atrial fibrillation Atrial Fibrillation - complications Atrial Fibrillation - drug therapy Drug Therapy, Combination edoxaban elderly Humans Male non-vitamin k oral anticoagulant obesity Obesity, Morbid - complications plasma levels Pyridines - administration & dosage Pyridines - pharmacokinetics Thiazoles - administration & dosage Thiazoles - pharmacokinetics |
title | Edoxaban in elderly patient with morbid obesity and atrial fibrillation: the role of plasma levels evaluation for selecting the appropriate dose |
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