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Electrolyte disorders in stable renal allograft recipients
Acid base and electrolyte disorders are frequently reported in the early period after renal transplantation. No comprehensive data exist on the prevalence and patterns of, and contributing factors to, electrolyte disturbances in patients with stable long-term allograft function. We analysed 576 rena...
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Published in: | Swiss medical weekly 2020-10, Vol.150 (4344), p.w20366-w20366 |
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creator | Beilhack, Georg Lindner, Gregor Funk, Georg-Christian Monteforte, Rossella Schwarz, Christoph |
description | Acid base and electrolyte disorders are frequently reported in the early period after renal transplantation. No comprehensive data exist on the prevalence and patterns of, and contributing factors to, electrolyte disturbances in patients with stable long-term allograft function.
We analysed 576 renal transplant recipients (serum creatinine level |
doi_str_mv | 10.4414/smw.2020.20366 |
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We analysed 576 renal transplant recipients (serum creatinine level <2.0 mg/dl) in a cross-sectional study to evaluate the prevalence of electrolyte disorders and the risk factors associated with their occurrence.
A total of 369 patients (64%) of all allograft recipients (n = 576) showed at least one electrolyte and acid base disorder. The most abundant disorder was hypomagnesaemia (25%, n = 143), followed by hyperkalaemia (12.8%, n = 74), hypercalcaemia (12%, n = 69), hypophosphataemia (11.6%, n = 67), metabolic acidosis (11.1%, n = 61) and hyponatraemia (9%, n = 52). All other electrolyte disorders were rare (<6%). In most cases the electrolyte disorders could be classified as mild. Forty percent of the cases had a combined disorder, but without a preferential pattern of combinations. In a multivariate logistic regression analysis, the most important factors contributing significantly to the occurrence of electrolyte disorders were renal function and concomitant medications.
Acid base and electrolyte disorders are frequently observed in stable renal allograft recipients, but are usually mild. A combination of two or more electrolyte abnormalities often occurs, although no predominant pattern of a unique combination of electrolyte disorder is recognizable. &nbsp.</description><identifier>ISSN: 1424-3997</identifier><identifier>EISSN: 1424-3997</identifier><identifier>DOI: 10.4414/smw.2020.20366</identifier><identifier>PMID: 33181857</identifier><language>eng</language><publisher>Switzerland: SMW supporting association (Trägerverein Swiss Medical Weekly SMW)</publisher><subject>hyperkalaemia ; hypomagnesaemia ; hyponatraemia ; hypophosphataemia ; kidney transplantation</subject><ispartof>Swiss medical weekly, 2020-10, Vol.150 (4344), p.w20366-w20366</ispartof><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3866-644401a5f42a2e2358c26155edbc5dfb4ab42580b2dbfb4bda9101963588d3513</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/33181857$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Beilhack, Georg</creatorcontrib><creatorcontrib>Lindner, Gregor</creatorcontrib><creatorcontrib>Funk, Georg-Christian</creatorcontrib><creatorcontrib>Monteforte, Rossella</creatorcontrib><creatorcontrib>Schwarz, Christoph</creatorcontrib><title>Electrolyte disorders in stable renal allograft recipients</title><title>Swiss medical weekly</title><addtitle>Swiss Med Wkly</addtitle><description>Acid base and electrolyte disorders are frequently reported in the early period after renal transplantation. No comprehensive data exist on the prevalence and patterns of, and contributing factors to, electrolyte disturbances in patients with stable long-term allograft function.
We analysed 576 renal transplant recipients (serum creatinine level <2.0 mg/dl) in a cross-sectional study to evaluate the prevalence of electrolyte disorders and the risk factors associated with their occurrence.
A total of 369 patients (64%) of all allograft recipients (n = 576) showed at least one electrolyte and acid base disorder. The most abundant disorder was hypomagnesaemia (25%, n = 143), followed by hyperkalaemia (12.8%, n = 74), hypercalcaemia (12%, n = 69), hypophosphataemia (11.6%, n = 67), metabolic acidosis (11.1%, n = 61) and hyponatraemia (9%, n = 52). All other electrolyte disorders were rare (<6%). In most cases the electrolyte disorders could be classified as mild. Forty percent of the cases had a combined disorder, but without a preferential pattern of combinations. In a multivariate logistic regression analysis, the most important factors contributing significantly to the occurrence of electrolyte disorders were renal function and concomitant medications.
Acid base and electrolyte disorders are frequently observed in stable renal allograft recipients, but are usually mild. A combination of two or more electrolyte abnormalities often occurs, although no predominant pattern of a unique combination of electrolyte disorder is recognizable. &nbsp.</description><subject>hyperkalaemia</subject><subject>hypomagnesaemia</subject><subject>hyponatraemia</subject><subject>hypophosphataemia</subject><subject>kidney transplantation</subject><issn>1424-3997</issn><issn>1424-3997</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><sourceid>DOA</sourceid><recordid>eNpNkMtLAzEQxoMoVqtXj7JHL6157643kfoAwYuewySZLVvSpiZbxP_e9KF4mcwXvnwz-RFyxehUSiZv8_JryimnpQitj8gZk1xORNvWx__6ETnPeUEpbzRTp2QkBGtYo-ozcjcL6IYUw_eAle9zTB5TrvpVlQewAauEKwgVhBDnCbqhaNeve1wN-YKcdBAyXh7OMfl4nL0_PE9e355eHu5fJ040Wk-0lJIyUJ3kwJEL1ThetlDorVO-sxKs5KqhlntblPXQMspaXYyNF4qJMXnZ5_oIC7NO_RLSt4nQm91FTHMDaehdQCNZ-awSrgZ0UgBrsLZWU_DIW62FK1k3-6x1ip8bzINZ9tlhCLDCuMmGS01rXZasi3W6t7oUc07Y_Y1m1GzZm8LebNmbHfvy4PqQvbFL9H_2X9jiBxzHfn0</recordid><startdate>20201019</startdate><enddate>20201019</enddate><creator>Beilhack, Georg</creator><creator>Lindner, Gregor</creator><creator>Funk, Georg-Christian</creator><creator>Monteforte, Rossella</creator><creator>Schwarz, Christoph</creator><general>SMW supporting association (Trägerverein Swiss Medical Weekly SMW)</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>DOA</scope></search><sort><creationdate>20201019</creationdate><title>Electrolyte disorders in stable renal allograft recipients</title><author>Beilhack, Georg ; Lindner, Gregor ; Funk, Georg-Christian ; Monteforte, Rossella ; Schwarz, Christoph</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3866-644401a5f42a2e2358c26155edbc5dfb4ab42580b2dbfb4bda9101963588d3513</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>hyperkalaemia</topic><topic>hypomagnesaemia</topic><topic>hyponatraemia</topic><topic>hypophosphataemia</topic><topic>kidney transplantation</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Beilhack, Georg</creatorcontrib><creatorcontrib>Lindner, Gregor</creatorcontrib><creatorcontrib>Funk, Georg-Christian</creatorcontrib><creatorcontrib>Monteforte, Rossella</creatorcontrib><creatorcontrib>Schwarz, Christoph</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>DOAJ Directory of Open Access Journals</collection><jtitle>Swiss medical weekly</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Beilhack, Georg</au><au>Lindner, Gregor</au><au>Funk, Georg-Christian</au><au>Monteforte, Rossella</au><au>Schwarz, Christoph</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Electrolyte disorders in stable renal allograft recipients</atitle><jtitle>Swiss medical weekly</jtitle><addtitle>Swiss Med Wkly</addtitle><date>2020-10-19</date><risdate>2020</risdate><volume>150</volume><issue>4344</issue><spage>w20366</spage><epage>w20366</epage><pages>w20366-w20366</pages><issn>1424-3997</issn><eissn>1424-3997</eissn><abstract>Acid base and electrolyte disorders are frequently reported in the early period after renal transplantation. No comprehensive data exist on the prevalence and patterns of, and contributing factors to, electrolyte disturbances in patients with stable long-term allograft function.
We analysed 576 renal transplant recipients (serum creatinine level <2.0 mg/dl) in a cross-sectional study to evaluate the prevalence of electrolyte disorders and the risk factors associated with their occurrence.
A total of 369 patients (64%) of all allograft recipients (n = 576) showed at least one electrolyte and acid base disorder. The most abundant disorder was hypomagnesaemia (25%, n = 143), followed by hyperkalaemia (12.8%, n = 74), hypercalcaemia (12%, n = 69), hypophosphataemia (11.6%, n = 67), metabolic acidosis (11.1%, n = 61) and hyponatraemia (9%, n = 52). All other electrolyte disorders were rare (<6%). In most cases the electrolyte disorders could be classified as mild. Forty percent of the cases had a combined disorder, but without a preferential pattern of combinations. In a multivariate logistic regression analysis, the most important factors contributing significantly to the occurrence of electrolyte disorders were renal function and concomitant medications.
Acid base and electrolyte disorders are frequently observed in stable renal allograft recipients, but are usually mild. A combination of two or more electrolyte abnormalities often occurs, although no predominant pattern of a unique combination of electrolyte disorder is recognizable. &nbsp.</abstract><cop>Switzerland</cop><pub>SMW supporting association (Trägerverein Swiss Medical Weekly SMW)</pub><pmid>33181857</pmid><doi>10.4414/smw.2020.20366</doi><oa>free_for_read</oa></addata></record> |
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source | Alma/SFX Local Collection |
subjects | hyperkalaemia hypomagnesaemia hyponatraemia hypophosphataemia kidney transplantation |
title | Electrolyte disorders in stable renal allograft recipients |
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