Characteristics and complications of fracture in older adults with chronic kidney disease: a cross-sectional study

• Published in: Journal of orthopaedic surgery and research 2022-08, Vol.17 (1), p.1-377, Article 377
• Main Authors: Meng, Yao, Fu, Mingming, Guo, Junfei, Wang, Zhiqian, Zhang, Yingze, Hou, Zhiyong
• Format: Article
• Language: English
• Subjects: Age groups; Aged patients; Anemia; Calcification; Cardiovascular calcification; Cardiovascular diseases; Chronic kidney disease; Chronic kidney failure; Cross-sectional studies; Disease susceptibility; Estrogens; Fracture; Fractures; Heart failure; Hemodialysis; Hemoglobin; Hypertension; Internal medicine; Kidney diseases; Medical research; Medicine, Experimental; Older adults; Older people; Orthopedics; Patients; Risk factors; Womens health
• ISSN: 1749-799X; 1749-799X
• DOI: 10.1186/s13018-022-03253-8

Background The aim of this study was to analyze the clinical characteristics of older fracture patients with chronic kidney disease (CKD) and to determine the risk factors of perioperative cardiovascular complications. Methods We retrospectively reviewed clinical data of older fracture patients with CKD admitted to the Third Hospital of Hebei Medical University from January 2016 to October 2021. The data we collected included baseline characteristics and complications. We finally determined the risk factors of perioperative cardiovascular complications by using logistic regression. Results We ended up enrolling 224 patients, and there were 91 (40.6%) males and 133 (59.4%) females, with a median age of 79 years. 80-84 years old was the age group with high incidence of fracture. The majority of fracture occurred indoors (130 cases, 58.0%) and morning (98 cases, 43.8%). Hip fracture was most common (183 cases, 81.7%), of which femoral neck fracture (101 cases, 45.0%) was the most prevalent. The most common comorbid condition was hypertension (171 cases, 76.3%), and anemia was the most common complication (148 cases, 66.1%). Age [greater than or equal to] 80 years (OR = 2.023, 95% CI 1.110-3.688), previously combined with cardiovascular calcification (OR = 1.901, 95% CI 1.047-3.451) and admission hemoglobin level < 100 g/L (OR = 3.191, 95% CI 1.744-5.838) were independent risk factors of perioperative cardiovascular disease (CVD). Conclusion It was especially necessary to enhance fracture prevention for CKD. Patients whose age older than 80, hemoglobin less than 100 g/L on admission and have previous cardiovascular calcification are more likely to develop perioperative CVD. Such patients require reasonable decisions during the perioperative period to avoid the occurrence of CVD. Keywords: Chronic kidney disease, Fracture, Older adults, Cardiovascular calcification, Hemoglobin