Characteristics and local risk factors of community-acquired and health-care-associated Staphylococcus aureus pneumonia

• Published in: Scientific reports 2022-11, Vol.12 (1), p.18670-8, Article 18670
• Main Authors: Lee, Li-Na, Chou, Wen-Ru, Wang, Jann-Yuan, Kuo, Yen-Liang, Chang, Chi-Yueh, Lee, Yi-Chien, Tung, Shao-Hsien, Tsao, Wen-Ching, Chao, Ke-Yun, Liu, Wei-Lun
• Format: Article
• Language: English
• Subjects: 692/499; 692/699; Adult; Aged; Anti-Bacterial Agents - therapeutic use; Blood; Cirrhosis; Community-Acquired Infections - diagnosis; Cross Infection - drug therapy; Diabetes mellitus; Female; Health care; Healthcare-Associated Pneumonia - drug therapy; Hemodialysis; Humanities and Social Sciences; Humans; Liver cirrhosis; Middle Aged; Mortality; multidisciplinary; Multivariate analysis; Myocardial infarction; Pleural effusion; Pneumonia; Pneumonia - drug therapy; Pneumonia, Staphylococcal - drug therapy; Pneumonia, Staphylococcal - epidemiology; Retrospective Studies; Risk Factors; Science; Science (multidisciplinary); Skin diseases; Skin lesions; Staphylococcus aureus; Streptococcus infections; Streptococcus pneumoniae
• ISSN: 2045-2322; 2045-2322
• DOI: 10.1038/s41598-022-23246-1

This study aims at identifying characteristics, risk factors and mortality of community-acquired (CAP) and health-care-associated pneumonia (HCAP) by Staphylococcus aureus ( S . aureus ). We retrieved adults with S. aureus CAP or HCAP diagnosed by blood or pleural effusion culture in 2.6 years, and compared with those of Streptococcus pneumoniae ( S. pneumoniae ) CAP or HCAP diagnosed by blood or respiratory culture, or urine antigen. We found 18 patients with CAP and 9 HCAP due to S. aureus (female 33%, 66.6 ± 12.4 years-old), and 48 patients with CAP and 15 HCAP due to S pneumoniae (female 41%, 69.5 ± 17.5 years). Diabetes mellitus (52% vs. 24%, p  = 0.019), hemodialysis (11% vs. 0%, p  = 0.046), skin lesions (44% vs. 0%, p