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Fatigue in lung cancer patients: symptom burden and management of challenges

Lung cancer (LC) remains the most common cause of cancer death in several countries across the world. Fatigue is the most frequently reported symptom in LC patients throughout the entire course of disease, and all international guidelines recommend early screening for cancer-related fatigue (CRF) an...

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Published in:Lung cancer (Auckland) 2016-01, Vol.7 (Issue 1), p.73-82
Main Authors: Carnio, Simona, Di Stefano, Rosario Francesco, Novello, Silvia
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Di Stefano, Rosario Francesco
Novello, Silvia
description Lung cancer (LC) remains the most common cause of cancer death in several countries across the world. Fatigue is the most frequently reported symptom in LC patients throughout the entire course of disease, and all international guidelines recommend early screening for cancer-related fatigue (CRF) and symptoms that can affect patients' quality of life. In patients with LC, fatigue belongs to the symptom cluster of pain, depression, and insomnia, which are commonly observed simultaneously, but are typically treated as separate although they may have common biological mechanisms. The treatment of CRF remains one of the difficult areas in the oncology field: scarce evidence supports pharmacological therapies, while some interesting data arising indicates alternative remedies and physical exercise seem to be one of the most effective approaches for CRF at any stage of LC.
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subjects Acupuncture
Cancer patients
Cancer therapies
Care and treatment
Chemotherapy
Chronic obstructive pulmonary disease
Clinical medicine
Clinical trials
Cytokines
Exercise
Fatigue
Feasibility studies
Health aspects
Lung cancer
Metastasis
Oncology
Pain
Palliative care
Patients
Physical fitness
Quality of life
Questionnaires
Review
Risk factors
Signal transduction
symptom cluster
Tumor necrosis factor-TNF
title Fatigue in lung cancer patients: symptom burden and management of challenges
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