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Fatigue in lung cancer patients: symptom burden and management of challenges
Lung cancer (LC) remains the most common cause of cancer death in several countries across the world. Fatigue is the most frequently reported symptom in LC patients throughout the entire course of disease, and all international guidelines recommend early screening for cancer-related fatigue (CRF) an...
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Published in: | Lung cancer (Auckland) 2016-01, Vol.7 (Issue 1), p.73-82 |
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description | Lung cancer (LC) remains the most common cause of cancer death in several countries across the world. Fatigue is the most frequently reported symptom in LC patients throughout the entire course of disease, and all international guidelines recommend early screening for cancer-related fatigue (CRF) and symptoms that can affect patients' quality of life. In patients with LC, fatigue belongs to the symptom cluster of pain, depression, and insomnia, which are commonly observed simultaneously, but are typically treated as separate although they may have common biological mechanisms. The treatment of CRF remains one of the difficult areas in the oncology field: scarce evidence supports pharmacological therapies, while some interesting data arising indicates alternative remedies and physical exercise seem to be one of the most effective approaches for CRF at any stage of LC. |
doi_str_mv | 10.2147/LCTT.S85334 |
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Fatigue is the most frequently reported symptom in LC patients throughout the entire course of disease, and all international guidelines recommend early screening for cancer-related fatigue (CRF) and symptoms that can affect patients' quality of life. In patients with LC, fatigue belongs to the symptom cluster of pain, depression, and insomnia, which are commonly observed simultaneously, but are typically treated as separate although they may have common biological mechanisms. The treatment of CRF remains one of the difficult areas in the oncology field: scarce evidence supports pharmacological therapies, while some interesting data arising indicates alternative remedies and physical exercise seem to be one of the most effective approaches for CRF at any stage of LC.</description><identifier>ISSN: 1179-2728</identifier><identifier>EISSN: 1179-2728</identifier><identifier>DOI: 10.2147/LCTT.S85334</identifier><identifier>PMID: 28210163</identifier><language>eng</language><publisher>New Zealand: Dove Medical Press Limited</publisher><subject>Acupuncture ; Cancer patients ; Cancer therapies ; Care and treatment ; Chemotherapy ; Chronic obstructive pulmonary disease ; Clinical medicine ; Clinical trials ; Cytokines ; Exercise ; Fatigue ; Feasibility studies ; Health aspects ; Lung cancer ; Metastasis ; Oncology ; Pain ; Palliative care ; Patients ; Physical fitness ; Quality of life ; Questionnaires ; Review ; Risk factors ; Signal transduction ; symptom cluster ; Tumor necrosis factor-TNF</subject><ispartof>Lung cancer (Auckland), 2016-01, Vol.7 (Issue 1), p.73-82</ispartof><rights>COPYRIGHT 2016 Dove Medical Press Limited</rights><rights>2016. 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This work is published and licensed by Dove Medical Press Limited 2016</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c573t-ab75acf0c18c8810e590f1e19e764d37bd6dbb5154a131838e68bec4d7e94cde3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.proquest.com/docview/2229655440/fulltextPDF?pq-origsite=primo$$EPDF$$P50$$Gproquest$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.proquest.com/docview/2229655440?pq-origsite=primo$$EHTML$$P50$$Gproquest$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,25753,27924,27925,37012,37013,44590,53791,53793,75126</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/28210163$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Carnio, Simona</creatorcontrib><creatorcontrib>Di Stefano, Rosario Francesco</creatorcontrib><creatorcontrib>Novello, Silvia</creatorcontrib><title>Fatigue in lung cancer patients: symptom burden and management of challenges</title><title>Lung cancer (Auckland)</title><addtitle>Lung Cancer (Auckl)</addtitle><description>Lung cancer (LC) remains the most common cause of cancer death in several countries across the world. Fatigue is the most frequently reported symptom in LC patients throughout the entire course of disease, and all international guidelines recommend early screening for cancer-related fatigue (CRF) and symptoms that can affect patients' quality of life. In patients with LC, fatigue belongs to the symptom cluster of pain, depression, and insomnia, which are commonly observed simultaneously, but are typically treated as separate although they may have common biological mechanisms. The treatment of CRF remains one of the difficult areas in the oncology field: scarce evidence supports pharmacological therapies, while some interesting data arising indicates alternative remedies and physical exercise seem to be one of the most effective approaches for CRF at any stage of LC.</description><subject>Acupuncture</subject><subject>Cancer patients</subject><subject>Cancer therapies</subject><subject>Care and treatment</subject><subject>Chemotherapy</subject><subject>Chronic obstructive pulmonary disease</subject><subject>Clinical medicine</subject><subject>Clinical trials</subject><subject>Cytokines</subject><subject>Exercise</subject><subject>Fatigue</subject><subject>Feasibility studies</subject><subject>Health aspects</subject><subject>Lung cancer</subject><subject>Metastasis</subject><subject>Oncology</subject><subject>Pain</subject><subject>Palliative care</subject><subject>Patients</subject><subject>Physical fitness</subject><subject>Quality of life</subject><subject>Questionnaires</subject><subject>Review</subject><subject>Risk factors</subject><subject>Signal transduction</subject><subject>symptom cluster</subject><subject>Tumor necrosis factor-TNF</subject><issn>1179-2728</issn><issn>1179-2728</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><sourceid>PIMPY</sourceid><sourceid>DOA</sourceid><recordid>eNptkt-LEzEQxxdRvOO8J99lQRBBWpPNj018EI7i6UHBB-tzyCaz25RsUpNd4f57U3uerZg8JMx85pvM8K2qlxgtG0zb9-vVZrP8Jhgh9El1iXErF03biKcn94vqOucdKosjxAR_Xl00osEIc3JZrW_15IYZahdqP4ehNjoYSPW-hCFM-UOd78f9FMe6m5OFUOtg61EHPcBY8nXsa7PV3kMYIL-onvXaZ7h-OK-q77efNqsvi_XXz3erm_XCsJZMC921TJseGSyMEBgBk6jHgCW0nFrSdpbbrmOYUY0JFkQAFx0YaluQ1FggV9XdUddGvVP75Ead7lXUTv0OxDQonSZnPCjaUIqEkQ3mnPaad8LiDgspBadc9KxofTxq7eduBGtKU0n7M9HzTHBbNcSfihGMuCRF4O2DQIo_ZsiTGl024L0OEOessOBScsLFAX39D7qLcwplVKppGskZK5_9Sw26NOBCH8u75iCqbhjinCGGRKGW_6HKtjA6EwP0rsTPCt6cFGxB-2mbo58nF0M-B98dQZNizgn6x2FgpA6mUwfTqaPpCv3qdH6P7B-LkV9xws6s</recordid><startdate>20160101</startdate><enddate>20160101</enddate><creator>Carnio, Simona</creator><creator>Di Stefano, Rosario Francesco</creator><creator>Novello, Silvia</creator><general>Dove Medical Press Limited</general><general>Taylor & Francis Ltd</general><general>Dove Medical Press</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>LK8</scope><scope>M0S</scope><scope>M2O</scope><scope>M7P</scope><scope>MBDVC</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>Q9U</scope><scope>7X8</scope><scope>5PM</scope><scope>DOA</scope></search><sort><creationdate>20160101</creationdate><title>Fatigue in lung cancer patients: symptom burden and management of challenges</title><author>Carnio, Simona ; Di Stefano, Rosario Francesco ; Novello, Silvia</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c573t-ab75acf0c18c8810e590f1e19e764d37bd6dbb5154a131838e68bec4d7e94cde3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>Acupuncture</topic><topic>Cancer patients</topic><topic>Cancer therapies</topic><topic>Care and treatment</topic><topic>Chemotherapy</topic><topic>Chronic obstructive pulmonary disease</topic><topic>Clinical medicine</topic><topic>Clinical trials</topic><topic>Cytokines</topic><topic>Exercise</topic><topic>Fatigue</topic><topic>Feasibility studies</topic><topic>Health aspects</topic><topic>Lung cancer</topic><topic>Metastasis</topic><topic>Oncology</topic><topic>Pain</topic><topic>Palliative care</topic><topic>Patients</topic><topic>Physical fitness</topic><topic>Quality of life</topic><topic>Questionnaires</topic><topic>Review</topic><topic>Risk factors</topic><topic>Signal transduction</topic><topic>symptom cluster</topic><topic>Tumor necrosis factor-TNF</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Carnio, Simona</creatorcontrib><creatorcontrib>Di Stefano, Rosario Francesco</creatorcontrib><creatorcontrib>Novello, Silvia</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>ProQuest_Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>ProQuest Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>ProQuest Biological Science Collection</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>ProQuest research library</collection><collection>Biological Science Database</collection><collection>Research Library (Corporate)</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><collection>DOAJ Directory of Open Access Journals</collection><jtitle>Lung cancer (Auckland)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Carnio, Simona</au><au>Di Stefano, Rosario Francesco</au><au>Novello, Silvia</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Fatigue in lung cancer patients: symptom burden and management of challenges</atitle><jtitle>Lung cancer (Auckland)</jtitle><addtitle>Lung Cancer (Auckl)</addtitle><date>2016-01-01</date><risdate>2016</risdate><volume>7</volume><issue>Issue 1</issue><spage>73</spage><epage>82</epage><pages>73-82</pages><issn>1179-2728</issn><eissn>1179-2728</eissn><abstract>Lung cancer (LC) remains the most common cause of cancer death in several countries across the world. 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subjects | Acupuncture Cancer patients Cancer therapies Care and treatment Chemotherapy Chronic obstructive pulmonary disease Clinical medicine Clinical trials Cytokines Exercise Fatigue Feasibility studies Health aspects Lung cancer Metastasis Oncology Pain Palliative care Patients Physical fitness Quality of life Questionnaires Review Risk factors Signal transduction symptom cluster Tumor necrosis factor-TNF |
title | Fatigue in lung cancer patients: symptom burden and management of challenges |
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