Diffusion tensor MR imaging evaluation of the corpus callosum of patients with multiple sclerosis Avaliação do corpo caloso em pacientes com esclerose múltipla através de imagens de RM por tensor de difusão

OBJECTIVE: To evaluate the fractional anisotropy (FA) values of the normal-appearing white matter of the corpus callosum (CC) in patients with relapsing-remitting multiple sclerosis (MS). METHOD: Fifty-seven patients with diagnosis of relapsing-remitting MS and 47 age- and gender-matched controls we...

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Bibliographic Details
Published in:Arquivos de neuro-psiquiatria 2008-09, Vol.66 (3a), p.449-453
Main Authors: Fernanda Rueda, Luiz Celso Hygino Jr, Romeu Cortês Domingues, Cláudia C. Vasconcelos, Regina M. Papais-Alvarenga, Emerson L. Gasparetto
Format: Article
Language:English
Subjects:
anisotropia fracionada
diffusion tensor imaging
esclerose múltipla
fractional anisotropy
imagens de tensor de difusão
multiple sclerosis
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Summary:OBJECTIVE: To evaluate the fractional anisotropy (FA) values of the normal-appearing white matter of the corpus callosum (CC) in patients with relapsing-remitting multiple sclerosis (MS). METHOD: Fifty-seven patients with diagnosis of relapsing-remitting MS and 47 age- and gender-matched controls were studied. A conventional MR imaging protocol and a DTI sequence were performed. One neuroradiologist placed the regions of interest (ROIs) in the FA maps in five different portions of the normal-apearing CC (rostrum, genu, anterior and posterior portion of the body and splenium) in all cases. The statistical analysis was performed with the Mann-Whitney U test and p
ISSN:0004-282X
1678-4227
DOI:10.1590/S0004-282X2008000400001