Advancements in the Use of Hydrogels for Regenerative Medicine: Properties and Biomedical Applications

Due to their particular water absorption capacity, hydrogels are the most widely used scaffolds in biomedical studies to regenerate damaged tissue. Hydrogels can be used in tissue engineering to design scaffolds for three-dimensional cell culture, providing a novel alternative to the traditional two...

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Bibliographic Details
Published in:International journal of biomaterials 2022-11, Vol.2022, p.1-16
Main Authors: Revete, Andrea, Aparicio, Andrea, Cisterna, Bruno A., Revete, Javier, Luis, Luis, Ibarra, Ernesto, Segura González, Edwin A., Molino, Jay, Reginensi, Diego
Format: Article
Language:English
Subjects:
Biocompatibility
Biomechanics
Biomedical materials
Biomimetic materials
Brain
Brain injury
Brain tumors
Cell adhesion & migration
Cell culture
Cell growth
Cellulose
Central nervous system
Collagen
Composite materials
Extracellular matrix
Flexibility
Head injuries
Hydrogels
Immunology
Injuries
Material properties
Mechanical properties
Medicine
Neurodegenerative diseases
Physiological aspects
Polymers
Proteins
Regenerative medicine
Review
Scaffolds
Tissue engineering
Water absorption
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Summary:Due to their particular water absorption capacity, hydrogels are the most widely used scaffolds in biomedical studies to regenerate damaged tissue. Hydrogels can be used in tissue engineering to design scaffolds for three-dimensional cell culture, providing a novel alternative to the traditional two-dimensional cell culture as hydrogels have a three-dimensional biomimetic structure. This material property is crucial in regenerative medicine, especially for the nervous system, since it is a highly complex and delicate structure. Hydrogels can move quickly within the human body without physically disturbing the environment and possess essential biocompatible properties, as well as the ability to form a mimetic scaffold in situ. Therefore, hydrogels are perfect candidates for biomedical applications. Hydrogels represent a potential alternative to regenerating tissue lost after removing a brain tumor and/or brain injuries. This reason presents them as an exciting alternative to highly complex human physiological problems, such as injuries to the central nervous system and neurodegenerative disease.
ISSN:1687-8787
1687-8795
DOI:10.1155/2022/3606765