A strategy to synthesize pomegranate‐inspired hollow mesoporous molecularly imprinted nanoparticles by organic‐organic self‐assembly of dopamine

Molecularly imprinted polymers (MIPs) have attracted tremendous attention as potential materials, but the conventional MIPs preparation limits its application. In this study, a novel strategy to synthesize pomegranate‐inspired hollow mesoporous molecularly imprinted nanoparticles (HMMINs) by organic...

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Bibliographic Details
Published in:Nano select 2021-02, Vol.2 (2), p.328-337
Main Authors: Ji, Shunli, Huang, Jiawen, Li, Tengfei, Luo, Xi, Zheng, Feng
Format: Article
Language:English
Subjects:
Acids
Adsorption
Biocompatibility
Chemical composition
Chemical synthesis
chemo‐photothermal combined therapy
Dopamine
Drug carriers
hollow mesoporous polydopamine nanoparticles
Hydrocarbons
Imprinted polymers
molecularly imprinted polymers
Morphology
Nanoparticles
Polymerization
Polymers
selective adsorbent
Self-assembly
Sorbents
Sustained release
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Summary:Molecularly imprinted polymers (MIPs) have attracted tremendous attention as potential materials, but the conventional MIPs preparation limits its application. In this study, a novel strategy to synthesize pomegranate‐inspired hollow mesoporous molecularly imprinted nanoparticles (HMMINs) by organic‐organic self‐assembly of dopamine is reported. Benefiting from the unique chemical composition and architecture, the one‐pot synthesized HMMINs not only provide high imprinting efficiency and binding capacity, but possess biocompatibility, photothermal (PT) and sustained release effect, which indicates HMMIPDAs have great potential to be applied as a sorbent to increase the selectivity of analytes from complex matrices, and drug carrier for PT therapy to achieve sustained‐release of the drug. Pomegranate‐inspired hollow mesoporous molecularly imprinted nanoparticles were prepared by a one‐pot synthesis method as a sorbent to increase the selectivity of analytes from complex matrices, and drug carrier for PT therapy to achieve sustained‐release of the drug.
ISSN:2688-4011
2688-4011
DOI:10.1002/nano.202000185