Oxidant and antioxidant status in experimental rat testis after testicular torsion/detorsion

The aim of this study was to determine oxidative stress (OS) parameters after testicular torsion/detorsion in adult rats. In this experimental study, male adult Wistar rats were divided into four groups, each consisting of seven animals: group I-one hour right testicular torsion with subsequent orch...

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Bibliographic Details
Published in:International journal of fertility & sterility 2015-04, Vol.9 (1), p.121-128
Main Authors: Cvetkovic, Tatjana, Stankovic, Jablan, Najman, Stevo, Pavlovic, Dusica, Stokanovic, Dragana, Vlajkovic, Slobodan, Dakovic-Bjelakovic, Marija, Cukuranovic, Jovana, Zivkovic, Vladimir, Stefanovic, Vladisav
Format: Article
Language:English
Subjects:
advanced oxidation protein products
Original
oxidative stress
reperfusion injury
spermatic cord torsion
testis
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Summary:The aim of this study was to determine oxidative stress (OS) parameters after testicular torsion/detorsion in adult rats. In this experimental study, male adult Wistar rats were divided into four groups, each consisting of seven animals: group I-one hour right testicular torsion with subsequent orchiectomy, group II-one hour right testicular torsion followed by detorsion, group III-unilateral right-sided orchiectomy without previous torsion and group IV-control. After 30 days, bilateral orchiectomies were performed in rats with both testes and unilateral orchiectomies in rats with single testicles. Parameters of OS were determined in testicular tissue and in plasma. Plasma concentrations of advanced oxidation protein products (AOPP) and thiobarbituric acid reactive substances (TBARS) were higher (p
ISSN:2008-076X
2008-0778
DOI:10.22074/ijfs.2015.4216