United Kingdom Early Detection Initiative (UK-EDI): protocol for establishing a national multicentre cohort of individuals with new-onset diabetes for early detection of pancreatic cancer

IntroductionPancreatic cancer is a leading cause of cancer deaths worldwide. Screening for this disease has potential to improve survival. It is not feasible, with current screening modalities, to screen the asymptomatic adult population. However, screening of individuals in high-risk groups is reco...

Full description

Saved in:
Bibliographic Details
Published in:BMJ open 2022-10, Vol.12 (10), p.e068010-e068010
Main Authors: Oldfield, Lucy, Stott, Martyn, Hanson, Robert, Jackson, Richard J, Reynolds, William, Chandran-Gorner, Vatshala, Van Der Meer, Robert, Alison, Laurence, Tejeiro, Ricardo, Purewal, Tejpal, Ghaneh, Paula, Palmer, Daniel, Greenhalf, William, Halloran, Chris, Costello, Eithne
Format: Article
Language:English
Subjects:
Aged
Biomarkers
Cohort Studies
Diabetes
diabetes & endocrinology
Diabetes Mellitus - diagnosis
Diabetes Mellitus - epidemiology
Early Detection of Cancer - methods
Gastroenterology and Hepatology
Glycated Hemoglobin
Hemoglobin
hepatobiliary tumours
Humans
Informed consent
Laboratories
Medical prognosis
Middle Aged
Multicenter Studies as Topic
Observational Studies as Topic
Pancreatic cancer
pancreatic disease
Pancreatic Neoplasms
Pancreatic Neoplasms - diagnosis
Pancreatic Neoplasms - epidemiology
Population
Primary care
Prospective Studies
Quality of life
Questionnaires
United Kingdom - epidemiology
Weight control
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:IntroductionPancreatic cancer is a leading cause of cancer deaths worldwide. Screening for this disease has potential to improve survival. It is not feasible, with current screening modalities, to screen the asymptomatic adult population. However, screening of individuals in high-risk groups is recommended. Our study aims to provide resources and data that will inform strategies to screen individuals with new-onset diabetes (NOD) for pancreatic cancer.Methods and analysisThe United Kingdom Early Detection Initiative (UK-EDI) for pancreatic cancer is a national, prospective, observational cohort study that aims to recruit 2500 individuals with NOD (
ISSN:2044-6055
2044-6055
DOI:10.1136/bmjopen-2022-068010