Medicinal Plants Extracts with Antiangiogenic Activity: Where Is the Link?

Angiogenesis is a strictly controlled process defined as the formation of new blood vessels essential for certain physiologic and pathologic conditions where the latter includes tumor growth, development, and metastasis. Thus, inhibiting angiogenesis along with other anticancer strategies such as ch...

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Bibliographic Details
Published in:Advanced pharmaceutical bulletin 2020-07, Vol.10 (3), p.370-378
Main Authors: Hoseinkhani, Zohreh, Norooznezhad, Fathemeh, Rastegari-Pouyani, Mohsen, Mansouri, Kamran
Format: Article
Language:English
Subjects:
Angiogenesis
Apoptosis
Cancer therapies
Cell cycle
Chemical compounds
Chemotherapy
Kinases
Melanoma
Metastasis
natural compounds
plant extract
Review
Rice
Tumors
Vascular endothelial growth factor
Wound healing
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Summary:Angiogenesis is a strictly controlled process defined as the formation of new blood vessels essential for certain physiologic and pathologic conditions where the latter includes tumor growth, development, and metastasis. Thus, inhibiting angiogenesis along with other anticancer strategies such as chemotherapy seems to be invaluable for reaching an optimal outcome in cancer patients. It has been shown that some natural plant-derived compounds are capable of preventing the formation of these new blood vessels in the tumor and also inhibit the proliferation and growth of the cancer cells. In this review, we intend to introduce plants with anti-angiogenic properties and discuss their related features.
ISSN:2228-5881
2251-7308
DOI:10.34172/apb.2020.045