Uveitis reactivation following recombinant zoster vaccination

Describe three cases of uveitis reactivation following immunization with recombinant zoster vaccine (RZV). One patient developed reactivation of previously controlled multifocal choroiditis within one week of receiving RZV, requiring treatment with systemic corticosteroids. Two patients with previou...

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Bibliographic Details
Published in:American journal of ophthalmology case reports 2021-09, Vol.23, p.101115, Article 101115
Main Authors: Richards, Paige J., Wingelaar, Maxwell J., Armbrust, Karen R., Kopplin, Laura J.
Format: Article
Language:English
Subjects:
Autoimmune
Case Report
Multifocal choroiditis
Shingrix
Uveitis
Vaccine
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Summary:Describe three cases of uveitis reactivation following immunization with recombinant zoster vaccine (RZV). One patient developed reactivation of previously controlled multifocal choroiditis within one week of receiving RZV, requiring treatment with systemic corticosteroids. Two patients with previously controlled anterior uveitis developed new anterior segment inflammation after RZV; both were treated with topical corticosteroids and systemic antiviral therapy. Uveitis recurrence is an infrequent but serious potential ocular side effect of recombinant zoster vaccination.
ISSN:2451-9936
2451-9936
DOI:10.1016/j.ajoc.2021.101115