A Case of Disseminated Hypopigmented Keratoses Improved with Oral Acitretin

Disseminated hypopigmented keratosis is a distinct clinical entity and only few cases have been reported so far. Here, we present a 21-year-old man with almost 10-year history of hypopigmented, nonfollicular, keratotic lichenoid papules occurring on the extensor surfaces of the extremities, back and...

Full description

Saved in:
Bibliographic Details
Published in:Case reports in dermatological medicine 2017-01, Vol.2017 (2017), p.1-3
Main Authors: Uzun, S., Uzun, Sarp, Başsorgun, Cumhur İbrahim, Eskiocak, Ali Haydar
Format: Article
Language:English
Subjects:
Acitretin
Biopsy
Case Report
Case reports
Dermatology
Keratosis
Oral administration
Retinoids
Skin diseases
Vitamin A
Citations: Items that this one cites
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Disseminated hypopigmented keratosis is a distinct clinical entity and only few cases have been reported so far. Here, we present a 21-year-old man with almost 10-year history of hypopigmented, nonfollicular, keratotic lichenoid papules occurring on the extensor surfaces of the extremities, back and lumber region. Histopathological examination showed orthohyperkeratosis, irregular acanthosis, and sporadic papillomatosis with a normal amount of melanin and number of melanocytes. In addition, no marked inflammation or melanophages were seen. In order to exclude other possible causes, we performed laboratory tests and radiological examination which were all found to be normal. As the clinical and histopathological features of our patient were taken into account, it was considered to be compatible with the diagnosis of disseminated hypopigmented keratoses. So far, only topical therapies have been used with failure in the previously reported cases except one patient. Considering the extensive lesions, we treated the present patient with 5% salicylic acid in addition to oral acitretin and significant regression in all lesions was achieved, particularly on the keratosis.
ISSN:2090-6463
2090-6471
DOI:10.1155/2017/1617375