Online MR evaluation of inter- and intra-fraction uterus motions and bladder volume changes during cervical cancer external beam radiotherapy

The purpose of the study was to assess the uterus motions and bladder volume changes of fractional movements in cervical sites throughout the external beam radiotherapy (EBRT) treatment. A prospective online MR imaging tracking study was conducted in EBRT 43 patients with at least 4 scans during eac...

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Bibliographic Details
Published in:Radiation oncology (London, England) England), 2021-09, Vol.16 (1), p.179-179, Article 179
Main Authors: Li, Xu, Wang, Lizhen, Cui, Zhen, Li, Yukun, Liu, Pei, Wang, Yungang, Zhu, Jinhong, Zhu, Jianmin, Yin, Yong, Li, Zhenjiang
Format: Article
Language:English
Subjects:
Adult
Aged
Bladder
Bladder filling
Cancer
Cancer therapies
Cervical cancer
Cervix
Computed tomography
Cone-Beam Computed Tomography
Contouring
EBRT
Female
Humans
Inter-fractional and Intra-fractional bladder motion
Magnetic resonance imaging
Magnetic Resonance Imaging - methods
Medical imaging
Middle Aged
Movement
Online MRI
Patients
Planning
Prospective Studies
Radiation therapy
Radiotherapy, Image-Guided - methods
Scanners
Scanning
Simulation
Statistical analysis
Ultrasonic imaging
Ultrasound
Urinary Bladder - diagnostic imaging
Uterine cancer
Uterine Cervical Neoplasms - diagnostic imaging
Uterine Cervical Neoplasms - radiotherapy
Uterus
Uterus - diagnostic imaging
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Summary:The purpose of the study was to assess the uterus motions and bladder volume changes of fractional movements in cervical sites throughout the external beam radiotherapy (EBRT) treatment. A prospective online MR imaging tracking study was conducted in EBRT 43 patients with at least 4 scans during each treatment (before: ultrasound scan, MRI scan, CBCT scan, after: MRI scan) were included. In order to improve the treatment repeatability, each patient was instructed to empty the bladder and drink 500 ml water 1 h before CT simulation and each treatment. If the ultrasound scan result reached the CT simulation volume of bladder, the treatment began. Bladder was outlined on the T2 weighted axial sequence and CBCT image by the two observers to avoid the influence of contouring. The data of bladder volume and scanning time were accurately recorded. The bladder volumes, filling rates and uterus motion were retrospectively analyzed by MIM software. Inter-fraction variation of the bladder volume was significant (p 
ISSN:1748-717X
1748-717X
DOI:10.1186/s13014-021-01907-1