Diagnostic Value of Chest Computed Tomography Scan for Identification of Foreign Body Aspiration in Children: A Systematic Review and Meta-analysis

Introduction: Foreign body aspiration (FBA) is a common, life-threatening pediatric emergency and was shown to be associated with high risk of morbidity and mortality. This systematic review and meta-analysis aimed to investigate the diagnostic value of chest computed tomography (CT) scan for identi...

Full description

Saved in:
Bibliographic Details
Published in:Archives of academic emergency medicine 2024-09, Vol.13 (1)
Main Authors: Babak Goodarzy, Erfan Rahmani, Mehrdad Farrokhi, Reza Tavakoli, Atousa Moghadam Fard, Mohadese Ranjbaran Ghaleh, Yeganeh Ghalichebaf Yazdi, Reza Amani Beni, Erfan Ghadirzadeh, Fatemeh Afrazeh, Yalda Alipour Khabir, Sevda Alipour khabir, Paria Bakhtiyari, Javaneh Atighi, Mohammad Mahjoubi, Zahra Momeni, Hediyeh Jalayeri, Mohammad Hossein Hosseini, Behnam Hoorshad, Mehdi Tavakoli, Sepideh Seifi, Hamidreza Momeni, Amirhossein Mirbolook, Alireza Esmaili Jobani, Mozhdeh Mohammadi Visroudi, Aboulfazl Najafi, Zahrasadat Hosseini, Sobhan Aboulhassanzadeh, Negar Ajami, Sahel Ramezani, Mahdokht Sadat Manavi, Sina Safdari, Amirali Fallahian, Habib Azimi, Reza Zahedpasha, Ehsan Ranjbar, Mohammad Saeed Kahrizi, Lida Zare Lahijan
Format: Article
Language:English
Subjects:
Computed Tomography
CT Scan
Foreign Body Aspiration
Meta-analysis
Pediatrics
Respiratory Aspiration
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Introduction: Foreign body aspiration (FBA) is a common, life-threatening pediatric emergency and was shown to be associated with high risk of morbidity and mortality. This systematic review and meta-analysis aimed to investigate the diagnostic value of chest computed tomography (CT) scan for identification of FBA in children. Methods: From inception to May 2024, a systematic search was carried out across multiple databases including Medline, Scopus, and Web of Science, considering published papers in English language. Quality assessment of the included studies was performed using seven domains of Quality Assessment of Diagnostic Accuracy Studies-2 (QUADAS-2). Results: The systematic literature search yielded 7203 articles. The pooled sensitivity and specificity of chest CT scan for identification of FBA were 0.99 (95% CI: 0.98-0.99) and 0.97 (95% CI: 0.96-0.98), respectively. The pooled positive likelihood ratio was 10.12 (95% CI: 4.59-22.20), and pooled negative likelihood ratio was 0.05 (95% CI: 0.02-0.1). Furthermore, the area under the summarized receiver operating characteristic (SROC) curve was 0.98. Conclusion: Our meta-analysis revealed that despite high heterogeneity, in the diagnostic characteristics of chest CT scan among studies, it has high diagnostic value in identifying FBA in suspected pediatric cases.
ISSN:2645-4904
DOI:10.22037/aaem.v13i1.2431