The associations of ferritin, serum lipid and plasma glucose levels across pregnancy in women with gestational diabetes mellitus and newborn birth weight

• Published in: BMC pregnancy and childbirth 2023-06, Vol.23 (1), p.478-478, Article 478
• Main Authors: Ji, Jing, Wu, Pei, Li, Guohua, He, Zhangya, Wang, Shanshan, Yu, Wenlu, Li, Chao, Mi, Yang, Luo, Xiaoqin
• Format: Article
• Language: English
• Subjects: Birth weight; Children & youth; Cholesterol; Fasting plasma glucose; Ferritin; Gestational age; Gestational diabetes; Gestational diabetes mellitus; Glucose; High density lipoprotein; Hospitals; Lipid profile; Lipids; Metabolic disorders; Mothers; Multiple births; Newborn babies; Normal distribution; Plasma; Pregnancy; Regression analysis; Stillbirth; Trends; Womens health
• ISSN: 1471-2393; 1471-2393
• DOI: 10.1186/s12884-023-05806-z

Women with gestational diabetes mellitus (GDM) are at greater risk of abnormal birth weight. Since the level of biochemical indicators could often affect the intrauterine growth and development of the fetus, it is of great practical significance to understand the changes of biochemical levels across pregnancy in women with GDM and to find out the indicators that play an important role in predicting birth weight. The data source of this study was from the Xi'an Longitudinal Mother-Child Cohort study (XAMC), in which women with GDM with normal and high pre-pregnancy body mass index (BMI) and their newborns between January 1 and March 31 in 2018 were included. The data of ferritin, serum lipid profile and fasting plasma glucose (FPG) of mothers in the three trimesters of pregnancy, as well as birth weight of newborns were all collected from medical records. Multiple linear regression and multivariate logistic regression analyses were used to explore the association of the biochemical indexes and birth weight. A P value