Pseudomonas Phage PaBG-A Jumbo Member of an Old Parasite Family

Bacteriophage PaBG is a jumbo Myoviridae phage isolated from water of Lake Baikal. This phage has limited diffusion ability and thermal stability and infects a narrow range of strains. Therefore, it is hardly suitable for phage therapy applications. However, the analysis of the genome of PaBG presen...

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Bibliographic Details
Published in:Viruses 2020-07, Vol.12 (7), p.721
Main Authors: Evseev, Peter, Sykilinda, Nina, Gorshkova, Anna, Kurochkina, Lidia, Ziganshin, Rustam, Drucker, Valentin, Miroshnikov, Konstantin
Format: Article
Language:English
Subjects:
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Bacteria
bioinformatics
Genome, Viral
Genomes
Host Specificity
jumbo phage PaBG
molecular evolution
Morphology
Peptides
Phages
Phylogeny
Polyethylene glycol
Proteins
Proteomics
Pseudomonas
Pseudomonas aeruginosa - physiology
Pseudomonas aeruginosa - virology
Pseudomonas Phages - classification
Pseudomonas Phages - genetics
Pseudomonas Phages - isolation & purification
Pseudomonas Phages - physiology
Software
Thermal stability
Transmission electron microscopy
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Summary:Bacteriophage PaBG is a jumbo Myoviridae phage isolated from water of Lake Baikal. This phage has limited diffusion ability and thermal stability and infects a narrow range of strains. Therefore, it is hardly suitable for phage therapy applications. However, the analysis of the genome of PaBG presents a number of insights into the evolutionary history of this phage and jumbo phages in general. We suggest that PaBG represents an ancient group distantly related to all known classified families of phages.
ISSN:1999-4915
1999-4915
DOI:10.3390/v12070721