Long-chain noncoding RNA NEAT1 and autoimmune diseases

Autoimmune diseases result from the immune system’s response to autoantigen components, leading to damage to one’s own tissues and organs. The correlation between long noncoding RNAs (lncRNAs) and autoimmune diseases remains inconclusive. However, recent studies have revealed that the lncRNA nuclear...

Full description

Saved in:
Bibliographic Details
Published in:Exploration of immunology 2024-10, Vol.4 (5), p.616-623
Main Authors: Bao, Cheng, Tian, Li-Li, Li, Xiao-Liu, Xu, Min, Chen, Hong-Wei
Format: Article
Language:English
Subjects:
autoimmune disease
nuclear paraspeckle assembly transcript 1
systemic lupus erythematosus
Citations: Items that this one cites
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Autoimmune diseases result from the immune system’s response to autoantigen components, leading to damage to one’s own tissues and organs. The correlation between long noncoding RNAs (lncRNAs) and autoimmune diseases remains inconclusive. However, recent studies have revealed that the lncRNA nuclear paraspeckle assembly transcript 1 (NEAT1) plays a vital role in the development of various autoimmune diseases. Here, this review briefly summarizes the progress in understanding NEAT1 expression variations and related mechanisms in different autoimmune diseases, and discusses its potential use for future therapeutic applications.
ISSN:2768-6655
2768-6655
DOI:10.37349/ei.2024.00162