Repeatability of automated measurements by a new anterior segment optical coherence tomographer and biometer and agreement with standard devices

We assess repeatability of automatic measurements of a new anterior segment optical coherence tomographer and biometer (ANTERION) and their agreement with those provided by an anterior segment-optical coherence tomography device combined with Placido-disk corneal topography (MS-39) and a validated o...

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Bibliographic Details
Published in:Scientific reports 2021-01, Vol.11 (1), p.983-983, Article 983
Main Authors: Schiano-Lomoriello, Domenico, Hoffer, Kenneth J., Abicca, Irene, Savini, Giacomo
Format: Article
Language:English
Subjects:
692/308
692/699
692/700
Adult
Aged
Aged, 80 and over
Agreements
Astigmatism
Automation
Coefficient of variation
Cornea
Correlation coefficient
Female
Humanities and Social Sciences
Humans
Image Processing, Computer-Assisted - methods
Male
Middle Aged
multidisciplinary
Reference Standards
Reproducibility of Results
Science
Science (multidisciplinary)
Tomography, Optical Coherence - instrumentation
Young Adult
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Summary:We assess repeatability of automatic measurements of a new anterior segment optical coherence tomographer and biometer (ANTERION) and their agreement with those provided by an anterior segment-optical coherence tomography device combined with Placido-disk corneal topography (MS-39) and a validated optical biometer (IOLMaster 500). A consecutive series of patients underwent three measurements with ANTERION and one with MS-39. A subgroup of patients underwent biometry also with IOLMaster 500. Repeatability was assessed by means of within-subject standard deviation, coefficient of variation (COV), and intraclass correlation coefficient (ICC). Agreement was investigated with the 95% limits of agreement. Paired t-test and Wilcoxon matched-pairs test were performed to compare the measurements of the different devices. Repeatability of ANTERION measurements was high, with ICC > 0.98 for all parameters except astigmatism (0.963); all parameters apart from those related to astigmatism revealed a COV 
ISSN:2045-2322
2045-2322
DOI:10.1038/s41598-020-79674-4