Physical Activity, Immune System, and the Microbiome in Cardiovascular Disease

Cardiovascular health is a primary research focus, as it is a leading contributor to mortality and morbidity worldwide, and is prohibitively costly for healthcare. Atherosclerosis, the main driver of cardiovascular disease, is now recognized as an inflammatory disorder. Physical activity (PA) may ha...

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Bibliographic Details
Published in:Frontiers in physiology 2018-06, Vol.9, p.763-763
Main Authors: Fernandez, Dawn M, Clemente, Jose C, Giannarelli, Chiara
Format: Article
Language:English
Subjects:
atherosclerosis
cardiovascular disease
inflammation
microbiome
physical activity
Physiology
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Summary:Cardiovascular health is a primary research focus, as it is a leading contributor to mortality and morbidity worldwide, and is prohibitively costly for healthcare. Atherosclerosis, the main driver of cardiovascular disease, is now recognized as an inflammatory disorder. Physical activity (PA) may have a more important role in cardiovascular health than previously expected. This review overviews the contribution of PA to cardiovascular health, the inflammatory role of atherosclerosis, and the emerging evidence of the microbiome as a regulator of inflammation.
ISSN:1664-042X
1664-042X
DOI:10.3389/fphys.2018.00763