Effects of auriculotherapy on anxiety and biomarkers in Primary Health Care: a clinical trial

to assess the effects of auriculotherapy on anxiety and brain-derived neurotrophic factor (BDNF), neuron-specific enolase (NSE) and S100 calcium-binding protein B (S100B) serum levels in adults assisted in Primary Health Care. a pre-experimental pilot clinical trial. Information was obtained from 19...

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Published in:Revista Brasileira de Enfermagem 2023-01, Vol.76 (6), p.e20220728-9
Main Authors: Silva, Carina da, Siqueira, Letícia, Drago, Lívia Crespo, Lins, Elisa Mitkus Flores, Martins, Daniel Fernandes, Bobinski, Franciane
Format: Article
Language:English
Subjects:
Acupuncture
Adult
Anxiety
Anxiety - therapy
Anxiety disorders
Auriculotherapy
Biomarkers
Brain-Derived Neurotrophic Factor
Chinese medicine
Clinical trials
Enzymes
Evidence-based nursing
Herbal medicine
Humans
Mental disorders
Mental health
Nurses
NURSING
Nursing Assessment
Original
Primary care
Primary Health Care
Proteins
Quality of life
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Summary:to assess the effects of auriculotherapy on anxiety and brain-derived neurotrophic factor (BDNF), neuron-specific enolase (NSE) and S100 calcium-binding protein B (S100B) serum levels in adults assisted in Primary Health Care. a pre-experimental pilot clinical trial. Information was obtained from 19 patients using the State-Trait Anxiety Inventory (STAI) and analysis of BDNF, NSE and S100B serum levels. the pre-intervention anxiety score in the IDATE-Trait was 52.11±6.691 (CV 12.84%) and the assessment after auriculotherapy was significantly lower (43.72±8.141; CV 18.62%; P=0.0007). S100B levels were significantly reduced after auriculotherapy (from 64.03±72.18 to 54.03±68.53 pg/mL; CV 126.8%; P=0.0023). auriculotherapy effectively reduced anxiety levels. It proved to be safe and easy to apply, allowing nurses to perform this technique autonomously. A reduction of S100B was also evidenced, demonstrating possible prevention of neuronal damage.
ISSN:0034-7167
1984-0446
1984-0446
DOI:10.1590/0034-7167-2022-0728pt