Effects of auriculotherapy on anxiety and biomarkers in Primary Health Care: a clinical trial

to assess the effects of auriculotherapy on anxiety and brain-derived neurotrophic factor (BDNF), neuron-specific enolase (NSE) and S100 calcium-binding protein B (S100B) serum levels in adults assisted in Primary Health Care. a pre-experimental pilot clinical trial. Information was obtained from 19...

Full description

Saved in:
Bibliographic Details
Published in:Revista Brasileira de Enfermagem 2023-01, Vol.76 (6), p.e20220728-9
Main Authors: Silva, Carina da, Siqueira, Letícia, Drago, Lívia Crespo, Lins, Elisa Mitkus Flores, Martins, Daniel Fernandes, Bobinski, Franciane
Format: Article
Language:English
Subjects:
Acupuncture
Adult
Anxiety
Anxiety - therapy
Anxiety disorders
Auriculotherapy
Biomarkers
Brain-Derived Neurotrophic Factor
Chinese medicine
Clinical trials
Enzymes
Evidence-based nursing
Herbal medicine
Humans
Mental disorders
Mental health
Nurses
NURSING
Nursing Assessment
Original
Primary care
Primary Health Care
Proteins
Quality of life
Citations: Items that this one cites
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
cited_by
cites cdi_FETCH-LOGICAL-c493t-74f2b458d524d27a25eeb197443351e054e2ccf43ca08d2434d4b420004b4eea3
container_end_page 9
container_issue 6
container_start_page e20220728
container_title Revista Brasileira de Enfermagem
container_volume 76
creator Silva, Carina da
Siqueira, Letícia
Drago, Lívia Crespo
Lins, Elisa Mitkus Flores
Martins, Daniel Fernandes
Bobinski, Franciane
description to assess the effects of auriculotherapy on anxiety and brain-derived neurotrophic factor (BDNF), neuron-specific enolase (NSE) and S100 calcium-binding protein B (S100B) serum levels in adults assisted in Primary Health Care. a pre-experimental pilot clinical trial. Information was obtained from 19 patients using the State-Trait Anxiety Inventory (STAI) and analysis of BDNF, NSE and S100B serum levels. the pre-intervention anxiety score in the IDATE-Trait was 52.11±6.691 (CV 12.84%) and the assessment after auriculotherapy was significantly lower (43.72±8.141; CV 18.62%; P=0.0007). S100B levels were significantly reduced after auriculotherapy (from 64.03±72.18 to 54.03±68.53 pg/mL; CV 126.8%; P=0.0023). auriculotherapy effectively reduced anxiety levels. It proved to be safe and easy to apply, allowing nurses to perform this technique autonomously. A reduction of S100B was also evidenced, demonstrating possible prevention of neuronal damage.
doi_str_mv 10.1590/0034-7167-2022-0728pt
format article
fullrecord <record><control><sourceid>proquest_doaj_</sourceid><recordid>TN_cdi_doaj_primary_oai_doaj_org_article_458f422a580a4a80964fd1302a85d329</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><scielo_id>S0034_71672023001000208</scielo_id><doaj_id>oai_doaj_org_article_458f422a580a4a80964fd1302a85d329</doaj_id><sourcerecordid>2904391808</sourcerecordid><originalsourceid>FETCH-LOGICAL-c493t-74f2b458d524d27a25eeb197443351e054e2ccf43ca08d2434d4b420004b4eea3</originalsourceid><addsrcrecordid>eNpdUk1v1DAQjRCIVqU_AWSJC5eU8Vdic0FoVWilSiABR2RNHKfr4o0XO6nYf493U1aU02g88968Gb-qeknhgkoNbwG4qFvatDUDxmpomdpOT6pTqpWoQYjmaXV67DmpznP2HYCUlLNGPa9OuCqJaJvT6sflMDg7ZRIHgnPydg5xWruE2x2JI8Hxt3fTrsSedD5uMP10KRM_ki_Jl2xHrhyGaU1WmNw7gsQGP3qLgUzJY3hRPRswZHf-EM-q7x8vv62u6pvPn65XH25qKzSf6lYMrBNS9ZKJnrXIpHMd1a0QnEvqQArHrB0EtwiqZ4KLXnSCAUAJziE_q64X3j7indku0kxEbw4PMd0aTJO3wZkyZhCMoVSAAhXoRgw95cBQyZ4zXbguFq5svQvR3MU5jUW8-bq_qNlftBydA9Ayn4EqgPcLYDt3G9dbN04JwyMVjyujX5vbeG8oNFqCbArDmweGFH_NLk9m47N1IeDo4pwNU1rz8scHda__az3qYxoE11QdJMmly6aYc3LDUQ0Fs3eQOe5i9g4yi4MK7tW_qxxRf_3C_wAo4L3f</addsrcrecordid><sourcetype>Open Website</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2904391808</pqid></control><display><type>article</type><title>Effects of auriculotherapy on anxiety and biomarkers in Primary Health Care: a clinical trial</title><source>Publicly Available Content Database</source><source>SciELO</source><source>PubMed Central</source><creator>Silva, Carina da ; Siqueira, Letícia ; Drago, Lívia Crespo ; Lins, Elisa Mitkus Flores ; Martins, Daniel Fernandes ; Bobinski, Franciane</creator><creatorcontrib>Silva, Carina da ; Siqueira, Letícia ; Drago, Lívia Crespo ; Lins, Elisa Mitkus Flores ; Martins, Daniel Fernandes ; Bobinski, Franciane</creatorcontrib><description>to assess the effects of auriculotherapy on anxiety and brain-derived neurotrophic factor (BDNF), neuron-specific enolase (NSE) and S100 calcium-binding protein B (S100B) serum levels in adults assisted in Primary Health Care. a pre-experimental pilot clinical trial. Information was obtained from 19 patients using the State-Trait Anxiety Inventory (STAI) and analysis of BDNF, NSE and S100B serum levels. the pre-intervention anxiety score in the IDATE-Trait was 52.11±6.691 (CV 12.84%) and the assessment after auriculotherapy was significantly lower (43.72±8.141; CV 18.62%; P=0.0007). S100B levels were significantly reduced after auriculotherapy (from 64.03±72.18 to 54.03±68.53 pg/mL; CV 126.8%; P=0.0023). auriculotherapy effectively reduced anxiety levels. It proved to be safe and easy to apply, allowing nurses to perform this technique autonomously. A reduction of S100B was also evidenced, demonstrating possible prevention of neuronal damage.</description><identifier>ISSN: 0034-7167</identifier><identifier>ISSN: 1984-0446</identifier><identifier>EISSN: 1984-0446</identifier><identifier>DOI: 10.1590/0034-7167-2022-0728pt</identifier><identifier>PMID: 38055476</identifier><language>eng</language><publisher>Brazil: Associação Brasileira de Enfermagem</publisher><subject>Acupuncture ; Adult ; Anxiety ; Anxiety - therapy ; Anxiety disorders ; Auriculotherapy ; Biomarkers ; Brain-Derived Neurotrophic Factor ; Chinese medicine ; Clinical trials ; Enzymes ; Evidence-based nursing ; Herbal medicine ; Humans ; Mental disorders ; Mental health ; Nurses ; NURSING ; Nursing Assessment ; Original ; Primary care ; Primary Health Care ; Proteins ; Quality of life</subject><ispartof>Revista Brasileira de Enfermagem, 2023-01, Vol.76 (6), p.e20220728-9</ispartof><rights>2023. This work is published under https://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>This work is licensed under a Creative Commons Attribution 4.0 International License.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c493t-74f2b458d524d27a25eeb197443351e054e2ccf43ca08d2434d4b420004b4eea3</cites><orcidid>0000-0003-1484-3167 ; 0000-0002-3537-1712 ; 0000-0003-0202-6629 ; 0000-0002-3510-5625 ; 0000-0003-0404-3828 ; 0000-0002-6136-0523</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.proquest.com/docview/2904391808/fulltextPDF?pq-origsite=primo$$EPDF$$P50$$Gproquest$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.proquest.com/docview/2904391808?pq-origsite=primo$$EHTML$$P50$$Gproquest$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,24149,25752,27923,27924,37011,44589,53790,53792,74997</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/38055476$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Silva, Carina da</creatorcontrib><creatorcontrib>Siqueira, Letícia</creatorcontrib><creatorcontrib>Drago, Lívia Crespo</creatorcontrib><creatorcontrib>Lins, Elisa Mitkus Flores</creatorcontrib><creatorcontrib>Martins, Daniel Fernandes</creatorcontrib><creatorcontrib>Bobinski, Franciane</creatorcontrib><title>Effects of auriculotherapy on anxiety and biomarkers in Primary Health Care: a clinical trial</title><title>Revista Brasileira de Enfermagem</title><addtitle>Rev Bras Enferm</addtitle><description>to assess the effects of auriculotherapy on anxiety and brain-derived neurotrophic factor (BDNF), neuron-specific enolase (NSE) and S100 calcium-binding protein B (S100B) serum levels in adults assisted in Primary Health Care. a pre-experimental pilot clinical trial. Information was obtained from 19 patients using the State-Trait Anxiety Inventory (STAI) and analysis of BDNF, NSE and S100B serum levels. the pre-intervention anxiety score in the IDATE-Trait was 52.11±6.691 (CV 12.84%) and the assessment after auriculotherapy was significantly lower (43.72±8.141; CV 18.62%; P=0.0007). S100B levels were significantly reduced after auriculotherapy (from 64.03±72.18 to 54.03±68.53 pg/mL; CV 126.8%; P=0.0023). auriculotherapy effectively reduced anxiety levels. It proved to be safe and easy to apply, allowing nurses to perform this technique autonomously. A reduction of S100B was also evidenced, demonstrating possible prevention of neuronal damage.</description><subject>Acupuncture</subject><subject>Adult</subject><subject>Anxiety</subject><subject>Anxiety - therapy</subject><subject>Anxiety disorders</subject><subject>Auriculotherapy</subject><subject>Biomarkers</subject><subject>Brain-Derived Neurotrophic Factor</subject><subject>Chinese medicine</subject><subject>Clinical trials</subject><subject>Enzymes</subject><subject>Evidence-based nursing</subject><subject>Herbal medicine</subject><subject>Humans</subject><subject>Mental disorders</subject><subject>Mental health</subject><subject>Nurses</subject><subject>NURSING</subject><subject>Nursing Assessment</subject><subject>Original</subject><subject>Primary care</subject><subject>Primary Health Care</subject><subject>Proteins</subject><subject>Quality of life</subject><issn>0034-7167</issn><issn>1984-0446</issn><issn>1984-0446</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2023</creationdate><recordtype>article</recordtype><sourceid>PIMPY</sourceid><sourceid>DOA</sourceid><recordid>eNpdUk1v1DAQjRCIVqU_AWSJC5eU8Vdic0FoVWilSiABR2RNHKfr4o0XO6nYf493U1aU02g88968Gb-qeknhgkoNbwG4qFvatDUDxmpomdpOT6pTqpWoQYjmaXV67DmpznP2HYCUlLNGPa9OuCqJaJvT6sflMDg7ZRIHgnPydg5xWruE2x2JI8Hxt3fTrsSedD5uMP10KRM_ki_Jl2xHrhyGaU1WmNw7gsQGP3qLgUzJY3hRPRswZHf-EM-q7x8vv62u6pvPn65XH25qKzSf6lYMrBNS9ZKJnrXIpHMd1a0QnEvqQArHrB0EtwiqZ4KLXnSCAUAJziE_q64X3j7indku0kxEbw4PMd0aTJO3wZkyZhCMoVSAAhXoRgw95cBQyZ4zXbguFq5svQvR3MU5jUW8-bq_qNlftBydA9Ayn4EqgPcLYDt3G9dbN04JwyMVjyujX5vbeG8oNFqCbArDmweGFH_NLk9m47N1IeDo4pwNU1rz8scHda__az3qYxoE11QdJMmly6aYc3LDUQ0Fs3eQOe5i9g4yi4MK7tW_qxxRf_3C_wAo4L3f</recordid><startdate>20230101</startdate><enddate>20230101</enddate><creator>Silva, Carina da</creator><creator>Siqueira, Letícia</creator><creator>Drago, Lívia Crespo</creator><creator>Lins, Elisa Mitkus Flores</creator><creator>Martins, Daniel Fernandes</creator><creator>Bobinski, Franciane</creator><general>Associação Brasileira de Enfermagem</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AN0</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>CLZPN</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>M1P</scope><scope>NAPCQ</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>7X8</scope><scope>5PM</scope><scope>GPN</scope><scope>DOA</scope><orcidid>https://orcid.org/0000-0003-1484-3167</orcidid><orcidid>https://orcid.org/0000-0002-3537-1712</orcidid><orcidid>https://orcid.org/0000-0003-0202-6629</orcidid><orcidid>https://orcid.org/0000-0002-3510-5625</orcidid><orcidid>https://orcid.org/0000-0003-0404-3828</orcidid><orcidid>https://orcid.org/0000-0002-6136-0523</orcidid></search><sort><creationdate>20230101</creationdate><title>Effects of auriculotherapy on anxiety and biomarkers in Primary Health Care: a clinical trial</title><author>Silva, Carina da ; Siqueira, Letícia ; Drago, Lívia Crespo ; Lins, Elisa Mitkus Flores ; Martins, Daniel Fernandes ; Bobinski, Franciane</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c493t-74f2b458d524d27a25eeb197443351e054e2ccf43ca08d2434d4b420004b4eea3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2023</creationdate><topic>Acupuncture</topic><topic>Adult</topic><topic>Anxiety</topic><topic>Anxiety - therapy</topic><topic>Anxiety disorders</topic><topic>Auriculotherapy</topic><topic>Biomarkers</topic><topic>Brain-Derived Neurotrophic Factor</topic><topic>Chinese medicine</topic><topic>Clinical trials</topic><topic>Enzymes</topic><topic>Evidence-based nursing</topic><topic>Herbal medicine</topic><topic>Humans</topic><topic>Mental disorders</topic><topic>Mental health</topic><topic>Nurses</topic><topic>NURSING</topic><topic>Nursing Assessment</topic><topic>Original</topic><topic>Primary care</topic><topic>Primary Health Care</topic><topic>Proteins</topic><topic>Quality of life</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Silva, Carina da</creatorcontrib><creatorcontrib>Siqueira, Letícia</creatorcontrib><creatorcontrib>Drago, Lívia Crespo</creatorcontrib><creatorcontrib>Lins, Elisa Mitkus Flores</creatorcontrib><creatorcontrib>Martins, Daniel Fernandes</creatorcontrib><creatorcontrib>Bobinski, Franciane</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Nursing &amp; Allied Health Database</collection><collection>Health &amp; Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central</collection><collection>British Nursing Database</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Latin America &amp; Iberia Database</collection><collection>ProQuest Central</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health &amp; Medical Complete (Alumni)</collection><collection>Nursing &amp; Allied Health Database (Alumni Edition)</collection><collection>Health &amp; Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Nursing &amp; Allied Health Premium</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><collection>SciELO</collection><collection>Directory of Open Access Journals (DOAJ)</collection><jtitle>Revista Brasileira de Enfermagem</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Silva, Carina da</au><au>Siqueira, Letícia</au><au>Drago, Lívia Crespo</au><au>Lins, Elisa Mitkus Flores</au><au>Martins, Daniel Fernandes</au><au>Bobinski, Franciane</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Effects of auriculotherapy on anxiety and biomarkers in Primary Health Care: a clinical trial</atitle><jtitle>Revista Brasileira de Enfermagem</jtitle><addtitle>Rev Bras Enferm</addtitle><date>2023-01-01</date><risdate>2023</risdate><volume>76</volume><issue>6</issue><spage>e20220728</spage><epage>9</epage><pages>e20220728-9</pages><issn>0034-7167</issn><issn>1984-0446</issn><eissn>1984-0446</eissn><abstract>to assess the effects of auriculotherapy on anxiety and brain-derived neurotrophic factor (BDNF), neuron-specific enolase (NSE) and S100 calcium-binding protein B (S100B) serum levels in adults assisted in Primary Health Care. a pre-experimental pilot clinical trial. Information was obtained from 19 patients using the State-Trait Anxiety Inventory (STAI) and analysis of BDNF, NSE and S100B serum levels. the pre-intervention anxiety score in the IDATE-Trait was 52.11±6.691 (CV 12.84%) and the assessment after auriculotherapy was significantly lower (43.72±8.141; CV 18.62%; P=0.0007). S100B levels were significantly reduced after auriculotherapy (from 64.03±72.18 to 54.03±68.53 pg/mL; CV 126.8%; P=0.0023). auriculotherapy effectively reduced anxiety levels. It proved to be safe and easy to apply, allowing nurses to perform this technique autonomously. A reduction of S100B was also evidenced, demonstrating possible prevention of neuronal damage.</abstract><cop>Brazil</cop><pub>Associação Brasileira de Enfermagem</pub><pmid>38055476</pmid><doi>10.1590/0034-7167-2022-0728pt</doi><tpages>9</tpages><orcidid>https://orcid.org/0000-0003-1484-3167</orcidid><orcidid>https://orcid.org/0000-0002-3537-1712</orcidid><orcidid>https://orcid.org/0000-0003-0202-6629</orcidid><orcidid>https://orcid.org/0000-0002-3510-5625</orcidid><orcidid>https://orcid.org/0000-0003-0404-3828</orcidid><orcidid>https://orcid.org/0000-0002-6136-0523</orcidid><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 0034-7167
ispartof Revista Brasileira de Enfermagem, 2023-01, Vol.76 (6), p.e20220728-9
issn 0034-7167
1984-0446
1984-0446
language eng
recordid cdi_doaj_primary_oai_doaj_org_article_458f422a580a4a80964fd1302a85d329
source Publicly Available Content Database; SciELO; PubMed Central
subjects Acupuncture
Adult
Anxiety
Anxiety - therapy
Anxiety disorders
Auriculotherapy
Biomarkers
Brain-Derived Neurotrophic Factor
Chinese medicine
Clinical trials
Enzymes
Evidence-based nursing
Herbal medicine
Humans
Mental disorders
Mental health
Nurses
NURSING
Nursing Assessment
Original
Primary care
Primary Health Care
Proteins
Quality of life
title Effects of auriculotherapy on anxiety and biomarkers in Primary Health Care: a clinical trial
url http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-08T15%3A25%3A47IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_doaj_&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Effects%20of%20auriculotherapy%20on%20anxiety%20and%20biomarkers%20in%20Primary%20Health%20Care:%20a%20clinical%20trial&rft.jtitle=Revista%20Brasileira%20de%20Enfermagem&rft.au=Silva,%20Carina%20da&rft.date=2023-01-01&rft.volume=76&rft.issue=6&rft.spage=e20220728&rft.epage=9&rft.pages=e20220728-9&rft.issn=0034-7167&rft.eissn=1984-0446&rft_id=info:doi/10.1590/0034-7167-2022-0728pt&rft_dat=%3Cproquest_doaj_%3E2904391808%3C/proquest_doaj_%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c493t-74f2b458d524d27a25eeb197443351e054e2ccf43ca08d2434d4b420004b4eea3%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=2904391808&rft_id=info:pmid/38055476&rft_scielo_id=S0034_71672023001000208&rfr_iscdi=true