Association between metabolic healthy obesity and female infertility: the national health and nutrition examination survey, 2013-2020

• Published in: BMC public health 2023-08, Vol.23 (1), p.1524-1524, Article 1524
• Main Authors: Tang, Jing, Xu, Yun, Wang, Zhaorui, Ji, Xiaohui, Qiu, Qi, Mai, Zhuoyao, Huang, Jia, Ouyang, Nengyong, Chen, Hui
• Format: Article
• Language: English
• Subjects: Abnormalities; Analysis; Body mass index; Body weight; Care and treatment; Complications and side effects; Criteria; Diagnosis; Females; Health aspects; Health surveys; Infertility; Infertility, Female; Linearity; Metabolic healthy obesity; National Health and Nutrition Examination Survey; Nutrition; Obesity; Psychological aspects; Regression analysis; Regression models; Risk factors; Stress (Psychology); Surveys; Women; Womens health
• ISSN: 1471-2458; 1471-2458
• DOI: 10.1186/s12889-023-16397-x

Obesity has been confirmed to be associated with infertility. However, the association between metabolically healthy obesity (MHO), a subset of obesity with no metabolic abnormalities, and female infertility has not yet been investigated. This study aimed to examine the association between MHO and the risk of female infertility among United States. This study utilized a cross-sectional design and included 3542 women aged 20-45 years who were selected from the National Health and Nutrition Examination Survey (NHANES) 2013-2020 database. The association between MHO and the risk of infertility was evaluated using risk factor-adjusted logistic regression models. Higher BMI and WC were associated with increased infertility risk after adjusting for potential confounding factors (OR (95% CI): 1.04(1.02, 1.06), P = 0.001; OR (95% CI): 1.02 (1.01, 1.03), P