Alcoholic povidone-iodine or chlorhexidine-based antiseptic for the prevention of central venous catheter-related infections: In-use comparison

Highlights ► Chlorhexidine antiseptic has been compared to alcoholic povidone-iodine solution. ► Field test was conducted in critical care unit. ► Catheter related infection was measured and users opinion was asked. ► No major clinical advantage of chlorhexidine use was proved in infection preventio...

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Bibliographic Details
Published in:Journal of infection and public health 2012-03, Vol.5 (1), p.35-42
Main Authors: Girard, Raphaële, Comby, Christine, Jacques, Didier
Format: Article
Language:English
Subjects:
Anti-Infective Agents, Local - economics
Anti-Infective Agents, Local - therapeutic use
Antiseptic
Bacteremia - diagnosis
Bacteremia - epidemiology
Bacteremia - etiology
Catheter-Related Infections - prevention & control
Catheterization, Central Venous - adverse effects
Central venous catheter-related infections
Chlorhexidine - economics
Chlorhexidine - therapeutic use
Colony Count, Microbial
Cross Infection - prevention & control
Drug Costs
Equipment Contamination
Female
Humans
Infectious Disease
Intensive care
Intensive Care Units
Internal Medicine
Male
Povidone-Iodine - economics
Povidone-Iodine - therapeutic use
Proportional Hazards Models
Prospective Studies
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Summary:Highlights ► Chlorhexidine antiseptic has been compared to alcoholic povidone-iodine solution. ► Field test was conducted in critical care unit. ► Catheter related infection was measured and users opinion was asked. ► No major clinical advantage of chlorhexidine use was proved in infection prevention. ► No cost advantage was found, with a limited ease of use.
ISSN:1876-0341
1876-035X
DOI:10.1016/j.jiph.2011.10.007