Biogenic Ceria Nanoparticles (CeO 2 NPs) for Effective Photocatalytic and Cytotoxic Activity

Ceria nanoparticles (CeO NPs) are generally considered in various functional applications, such as catalysts in fuel cells, sensors, and antioxidant and oxidase-like enzymes in the biological environment. The CeO NPs were synthesized using the leaf extract-mediated hydrothermal technique. The synthe...

Full description

Saved in:
Bibliographic Details
Published in:Bioengineering (Basel) 2020-03, Vol.7 (1), p.26
Main Authors: Balaji, Siripireddy, Mandal, Badal Kumar, Vinod Kumar Reddy, L, Sen, Dwaipayan
Format: Article
Language:English
Subjects:
Antioxidants
Azo dyes
Bioengineering
Biotechnology
Cancer
Catalysis
Catalysts
ceo2 nps
Cerium oxides
cytotoxic activity
Cytotoxicity
Diameters
Dyes
e. globulus extract
Fuel cells
Gram-positive bacteria
human carcinoma cells
Light scattering
Morphology
Nanomaterials
Nanoparticles
Nitrates
Particle size
Photocatalysis
Photocatalysts
photocatalytic activity
Photodegradation
Photon correlation spectroscopy
Phytochemicals
Plant extracts
ros
Scanning electron microscopy
Spectrum analysis
Studies
Sunset
Surface area
Synthesis
Tumor cell lines
Ultraviolet radiation
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Ceria nanoparticles (CeO NPs) are generally considered in various functional applications, such as catalysts in fuel cells, sensors, and antioxidant and oxidase-like enzymes in the biological environment. The CeO NPs were synthesized using the leaf extract-mediated hydrothermal technique. The synthesized NPs were characterized by various analytical instruments including powder X-ray diffractometer (PXRD), scanning electron microscope (SEM), transmission electron microscope (TEM) and dynamic light scattering (DLS) analysis. The XRD results showed an average NPs sizes of 13.7 nm. Cytotoxic study results showed an IC value of 45.5 µg/L for A549 and 58.2 µg/L for HCT 116, indicating that CeO NPs are more toxic to A549 compared to HCT116 cell lines. The generation of ROS was responsible for its cytotoxic activity against cancer cell lines. Specific surface area (40.96 m /g) and pore diameter (7.8 nm) were measured using Brunauer-Emmett-Teller (BET) nitrogen adsorption-desorption isotherms. CeO NPs with a high surface area were used as photocatalyst in degrading sunset yellow (SY) dye under UV-irradiation and 97.3% of the dye was degraded within 90 min. These results suggest that the synthesized CeO NPs could be used as a good photocatalyst as well as a cytotoxic agent against human cancer cell lines.
ISSN:2306-5354
2306-5354
DOI:10.3390/bioengineering7010026