VASOplegia is Predicted by Preoperative Platelet-LEucocyte conGlomerate Indices in Cardiac Surgery (VASOPLEGICS): A retrospective single-center study

Background: Post-cardiotomy vasoplegia syndrome (VS) is often linked to an exaggerated inflammatory response to cardiopulmonary bypass (CPB). At the same time, the prognostic role of platelet-leucocyte indices (PLIs) and leucocyte indices (LIs), (platelet-lymphocyte ratio [PLR], systemic immune-infl...

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Bibliographic Details
Published in:Annals of cardiac anaesthesia 2022-10, Vol.25 (4), p.414-421
Main Authors: Magoon, Rohan, Kashav, Ramesh, Shri, Iti, Dey, Souvik, Walian, Ashish, Kohli, Jasvinder
Format: Article
Language:English
Subjects:
aggregate index of systemic inflammation
Blood
Blood platelets
cardiac surgery
Conglomerate corporations
Coronary artery bypass
Heart surgery
Inflammation
Lymphocytes
neutrophil-lymphocyte ratio
Neutrophils
Original
platelet-lymphocyte ratio
Surgery
systemic immune-inflammation index
systemic inflammation response index
vasoplegia syndrome
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Summary:Background: Post-cardiotomy vasoplegia syndrome (VS) is often linked to an exaggerated inflammatory response to cardiopulmonary bypass (CPB). At the same time, the prognostic role of platelet-leucocyte indices (PLIs) and leucocyte indices (LIs), (platelet-lymphocyte ratio [PLR], systemic immune-inflammation index [SII = platelet × neutrophil/lymphocyte], aggregate index of systemic inflammation [AISI = platelet × monocyte × neutrophil/lymphocyte], and neutrophil-lymphocyte ratio [NLR], systemic inflammation response index [SIRI = monocyte × neutrophil/lymphocyte), respectively] has been recently described in diverse inflammatory settings. Methods: The retrospective study was conducted to evaluate the VS predictive performance of PLIs and LIs in 1,045 adult patients undergoing elective cardiac surgery at a tertiary care center. VS was defined by mean blood pressure
ISSN:0971-9784
0974-5181
DOI:10.4103/aca.aca_54_21