Rapid Characterization and Identification of Chemical Constituents in Gentiana radix before and after Wine-Processed by UHPLC-LTQ-Orbitrap MSn

Gentiana radix is used in traditional Chinese medicine and has functions of clearing heat and drying dampness, as well as purging liver and gallbladder fire. A highly sensitive and effective strategy for rapid screening and identification of target constituents has been developed by using ultra high...

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Bibliographic Details
Published in:Molecules (Basel, Switzerland) Switzerland), 2018-12, Vol.23 (12), p.3222
Main Authors: Lv, Xin, Sun, Jian-Zhi, Xu, Shi-Zhao, Cai, Qian, Liu, Yu-Qiang
Format: Article
Language:English
Subjects:
characteristic fragmentation pathways
Complex systems
Constituents
Drying
Flavonoids
Gallbladder
Gentiana
Gentiana radix
Herbal medicine
High performance liquid chromatography
iridoids
Liquid chromatography
Mass spectrometry
Mass spectroscopy
Moisture content
Purging
UHPLC-LTQ-Orbitrap
Wine
wine-processing
xanthones
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Summary:Gentiana radix is used in traditional Chinese medicine and has functions of clearing heat and drying dampness, as well as purging liver and gallbladder fire. A highly sensitive and effective strategy for rapid screening and identification of target constituents has been developed by using ultra high-performance liquid chromatography coupled with linear ion trap-Orbitrap mass spectrometry (UHPLC-LTQ-Orbitrap) in crude and wine-processed Gentiana radix. Based on the accurate mass measurement (
ISSN:1420-3049
1420-3049
DOI:10.3390/molecules23123222