Analysis of Antidepressant, Benzodiazepine Anxiolytic, and Hypnotic Use When Treating Depression, Anxiety, and Aggression in Pain Clinic Patients Treated for Neuropathic Pain

Depression, anxiety, and aggression accompany neuropathic pain. Effective treatment of these comorbidities enhances the outcomes of pain management. Therefore, the study was designed to analyze the relationship between the intensity of depression, anxiety, and aggression and the pharmacotherapy appl...

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Bibliographic Details
Published in:Life (Basel, Switzerland) Switzerland), 2022-03, Vol.12 (3), p.433
Main Authors: Kolacz, Marcin, Kosson, Dariusz, Puchalska-Kowalczyk, Ewa, Mikaszewska-Sokolewicz, Malgorzata, Lisowska, Barbara, Malec-Milewska, Malgorzata
Format: Article
Language:English
Subjects:
Aggression
Analgesics
Anesthesiology
Anticonvulsants
Antidepressants
Anxiety
Anxiety disorders
Anxiolytics
Benzodiazepines
Clinics
depression
Drug therapy
Gender
Hypnotics
Intensive care
Mental depression
Narcotics
Neuralgia
neuropathic pain
Pain
Pain management
Patients
Psychotropic drugs
Questionnaires
Serotonin
Sleep
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Summary:Depression, anxiety, and aggression accompany neuropathic pain. Effective treatment of these comorbidities enhances the outcomes of pain management. Therefore, the study was designed to analyze the relationship between the intensity of depression, anxiety, and aggression and the pharmacotherapy applied in the daily practice of treating neuropathic pain. The aim of the study was to evaluate the frequency of using antidepressants (ADs), benzodiazepine anxiolytics (BDAs), and hypnotics, and the influence of administering these on the intensity of depression, anxiety, and aggression in patients diagnosed with neuropathic pain. A multi-center survey was conducted among 421 patients. An evaluation of the severity of depression, anxiety, and aggression was made using the Hospital Anxiety and Depression Scale-Modified Version (HADS-M). Among the patients treated due to neuropathic pain, ADs are used much more often than BDAs and hypnotics. Depression was well controlled, while anxiety was identified as a possible uncontrolled therapeutic problem in these patients, despite the correlation between the frequency of AD and hypnotics usage and the severity of anxiety. We also found that women show a higher level of intensity in both anxiety and depression, but this does not influence the frequency of their being administered ADs, BDAs, and hypnotics.
ISSN:2075-1729
2075-1729
DOI:10.3390/life12030433