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Bone marrow metastasis from advanced gastric cancer complicated with disseminated intravascular coagulation: a highly aggressive but manageable disease subtype
[...]inflammatory markers, such as white blood cells (WBC) counts, neutrophil counts, neutrophil to lymphocyte ratio (NLR) and C-reactive protein (CRP) level were increased in HAGC when effects of colony-stimulating factor and infection were excluded (Supplementary Table S3). [...]the ratio of pro-i...
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Published in: | Cancer communications (London, England) England), 2022-04, Vol.42 (4), p.350-354 |
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Main Authors: | , , , , , , , , , , , , , , , |
Format: | Article |
Language: | English |
Subjects: | |
Citations: | Items that this one cites Items that cite this one |
Online Access: | Get full text |
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Summary: | [...]inflammatory markers, such as white blood cells (WBC) counts, neutrophil counts, neutrophil to lymphocyte ratio (NLR) and C-reactive protein (CRP) level were increased in HAGC when effects of colony-stimulating factor and infection were excluded (Supplementary Table S3). [...]the ratio of pro-inflammatory M1 and anti-inflammatory M2 was elevated in the HAGC tumor immune environment (TIME), indicating an inflammatory environment [ 6] (Figure 1A, Supplementary Figure S1). [...]RNA-seq results demonstrated inflammatory response and IL-6-JAK-STAT3 signaling activation in HAGC patients (Figure 1C, Supplementary Figure S2). [...]most of these patients only received BSC and did not undergo further examinations; thus, indicating that the incidence of DIC in HAGC could be higher than estimated. |
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ISSN: | 2523-3548 2523-3548 |
DOI: | 10.1002/cac2.12277 |