A Rare Case of Light Chain Amyloidosis of the Gastrointestinal Tract

A 65-year-old Hispanic female presented with a one-year history of anorexia, nausea, early satiety, epigastric discomfort, and a 20 kg weight loss. Computed tomography (CT) demonstrated heterogeneous liver parenchyma. Upper endoscopy revealed large, fungating, infiltrative mass at the lesser gastric...

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Bibliographic Details
Published in:Case reports in surgery 2020-06, Vol.2020 (2020), p.1-4
Main Authors: Ben-David, Kfir, Schwartz, Michael, Coombs, Andre, Rapaka, Samuel, Cortez, Nathaly, Febres-Aldana, Christopher, Willet, Anna, Galarza-Fortuna, Gliceida M., Dvir, Kathrin, Goldberg, Robert
Format: Article
Language:English
Subjects:
Abdomen
Amyloidosis
Anorexia
Biopsy
Bone marrow
Cardiology
Case Report
Case reports
Chains
Computed tomography
Diagnosis
Endoscopy
Gastric cancer
Gastroenterology
Gastrointestinal diseases
Gastrointestinal system
Gastrointestinal tract
Heart failure
Hematology
Iron
Laparoscopy
Light
Liver
Medical prognosis
Multiple myeloma
Nausea
Parenchyma
Patients
Plasma
Satiety
Stroma
Transplants & implants
Weight loss
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Summary:A 65-year-old Hispanic female presented with a one-year history of anorexia, nausea, early satiety, epigastric discomfort, and a 20 kg weight loss. Computed tomography (CT) demonstrated heterogeneous liver parenchyma. Upper endoscopy revealed large, fungating, infiltrative mass at the lesser gastric curvature incisura, highly suspicious of gastric tumor; however, initial biopsy of the gastric mass was equivocal and an exploratory laparoscopy was performed. Repeated intraoperative biopsies of the gastric mass and of liver parenchyma demonstrated diffuse hyalinized stroma consistent with amyloid deposition, and a bone marrow biopsy confirmed the diagnosis of primary light chain (AL) amyloidosis.
ISSN:2090-6900
2090-6919
DOI:10.1155/2020/1921805