Mortality during 6 years of follow-up in relation to visual impairment and eye disease: results from a population-based cohort study of people aged 50 years and above in Nakuru, Kenya

ObjectiveTo estimate the association between (1) visual impairment (VI) and (2) eye disease and 6-year mortality risk within a cohort of elderly Kenyan people.Design, setting and participantsThe baseline of the Nakuru Posterior Segment Eye Disease Study was formed from a population-based survey of 4...

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Bibliographic Details
Published in:BMJ open 2019-06, Vol.9 (6), p.e029700-e029700
Main Authors: Kuper, Hannah, Mathenge, Wanjiku, Macleod, David, Foster, Allen, Gichangi, Michael, Rono, Hillary, Wing, Kevin, Weiss, Helen Anne, Bastawrous, Andrew, Burton, Matthew
Format: Article
Language:English
Subjects:
Age
Aged
Aging
Blood pressure
Cardiovascular disease
Cataract - mortality
Cataracts
Cohort analysis
Diabetes
Diabetic retinopathy
Diabetic Retinopathy - mortality
Epidemiology
Eye diseases
Eye Diseases - mortality
Family medical history
Female
Follow-Up Studies
Glaucoma
Health risk assessment
Humans
Kenya - epidemiology
Macular degeneration
Male
Middle Aged
Mortality
Odds Ratio
Population-based studies
Risk Factors
Socioeconomic factors
Vision Disorders - mortality
Visual impairment
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Summary:ObjectiveTo estimate the association between (1) visual impairment (VI) and (2) eye disease and 6-year mortality risk within a cohort of elderly Kenyan people.Design, setting and participantsThe baseline of the Nakuru Posterior Segment Eye Disease Study was formed from a population-based survey of 4318 participants aged ≥50 years, enrolled in 2007–2008. Ophthalmic and anthropometric examinations were undertaken on all participants at baseline, and a questionnaire was administered, including medical and ophthalmic history. Participants were retraced in 2013–2014 for a second examination. Vital status was recorded for all participants through information from community members. Cumulative incidence of mortality, and its relationship with baseline VI and types of eye disease was estimated. Inverse probability weighting was used to adjust for non-participation.Primary outcome measuresCumulative incidence of mortality in relation to VI level at baseline.ResultsOf the baseline sample, 2170 (50%) were re-examined at follow-up and 407 (10%) were known to have died (adjusted risk of 11.9% over 6 years). Compared to those with normal vision (visual acuity (VA) ≥6/12, risk=9.7%), the 6-year mortality risk was higher among people with VI (
ISSN:2044-6055
2044-6055
DOI:10.1136/bmjopen-2019-029700