Impacts of Macleaya cordata on Productive Performance, Expression of Growth-Related Genes, Hematological, and Biochemical Parameters in Turkey

Macleaya cordata (M. cordata) is a herbal plant that has abundant amounts of sanguinarine, which has many biomedical properties. The effects of M. cordata dietary supplementation on the productive performance, some blood constituents, and growth-related genes' expression were evaluated in turke...

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Published in:Frontiers in veterinary science 2022-07, Vol.9, p.873951-873951
Main Authors: Manaa, Eman A., Abdel-Latif, Mervat A., Ibraheim, Samya E., Sakr, Abdelaziz, Dawood, Mahmoud, Albadrani, Ghadeer M., El-kott, Attalla F., Abdel-Daim, Mohamed M., Shafik, Basant M.
Format: Article
Language:English
Subjects:
gene expression
growth performance
Macleaya cordata
Sangrovit
Turkey
Veterinary Science
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Summary:Macleaya cordata (M. cordata) is a herbal plant that has abundant amounts of sanguinarine, which has many biomedical properties. The effects of M. cordata dietary supplementation on the productive performance, some blood constituents, and growth-related genes' expression were evaluated in turkey. M. cordata extract was dietary supplemented to turkey at levels of 25, 50, and 100 ppm and a control group. Growth performance measurements (FBW, ADG, and FCR) and production efficiency factor for turkey (BPEF) were similar ( p > 0.05) in all supplemented groups. M. cordata has no adverse effects ( p > 0.05) on the birds' health regarding hematological (Hb, RBCs, WBCs, and PCV) and blood biochemical indices evaluating liver function, kidney function, and lipid profile. Moreover, the mRNA expression of growth-related genes, such as growth hormone receptor (GHR), insulin-like growth factor 1 (IGF-1), cyclooxygenase 3 (COX-3), adenine nucleotide translocase (ANT), and uncoupling protein 3 (UCP-3) were upregulated ( p < 0.001) in M. cordata treatments with the highest value for SG50 compared with the control group. We concluded that exogenous M. cordata dietary supplementation upregulated the expression of growth-related genes in turkey at a level of 50 ppm without adverse effects on their health status regarding hematological and biochemical indices.
ISSN:2297-1769
2297-1769
DOI:10.3389/fvets.2022.873951