Serum irisin level, insulin resistance, and lipid profiles in patients with hidradenitis suppurativa: a case-control study

Hidradenitis suppurativa is a chronic inflammatory skin disease of terminal follicular acroinfundibulum. This study aimed to evaluate serum irisin, plasma glucose, insulin, and lipid levels in hidradenitis suppurativa, and elucidate possible associations with disease activity, inflammatory, or metab...

Full description

Saved in:
Bibliographic Details
Published in:Anais brasileiros de dermatología 2020-11, Vol.95 (6), p.708-713
Main Authors: Özkur, Ezgi, Erdem, Yasemin, Altunay, İlknur Kıvanç, Demir, Damla, Dolu, Nurcihan Çalışkan, Serin, Erdinç, Çerman, Aslı Aksu
Format: Article
Language:English
Subjects:
Case-Control Studies
DERMATOLOGY
Hidradenitis Suppurativa
Humans
Insulin
Insulin Resistance
Investigation
Lipids
Metabolic diseases
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Hidradenitis suppurativa is a chronic inflammatory skin disease of terminal follicular acroinfundibulum. This study aimed to evaluate serum irisin, plasma glucose, insulin, and lipid levels in hidradenitis suppurativa, and elucidate possible associations with disease activity, inflammatory, or metabolic parameters. This case-control study included 37 patients (M/F: 9/28) and 37 sex-, age- and body mass index -matched healthy controls (M/F: 11/26). Demographic data, Hurley stage of disease, fasting glucose, insulin, total cholesterol, high density lipoprotein cholesterol, low-density lipoprotein cholesterol, triglycerides, C-reactive protein levels, erythrocyte sedimentation rate, hematologic parameters, and serum irisin were assessed. The hidradenitis suppurativa group had significantly higher waist circumference than controls (p
ISSN:0365-0596
1806-4841
1806-4841
DOI:10.1016/j.abd.2020.04.009