The development of microfabricated solenoids with magnetic cores for micromagnetic neural stimulation

Electrical stimulation via invasive microelectrodes is commonly used to treat a wide range of neurological and psychiatric conditions. Despite its remarkable success, the stimulation performance is not sustainable since the electrodes become encapsulated by gliosis due to foreign body reactions. Mag...

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Published in:Microsystems & nanoengineering 2021-11, Vol.7 (1), p.91-91, Article 91
Main Authors: Khalifa, Adam, Zaeimbashi, Mohsen, Zhou, Tony X., Abrishami, Seyed Mahdi, Sun, Neville, Park, Seunghyun, Šumarac, Tamara, Qu, Jason, Zohar, Inbar, Yacoby, Amir, Cash, Sydney, Sun, Nian X.
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Language:English
Subjects:
639/301/357/995
639/925/927/1007
Brain research
Electric contacts
Electrical stimuli
Electrodes
Engineering
Gliosis
Magnetic cores
Magnetic fields
Microelectrodes
Plating
Solenoids
Stimulation
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cited_by cdi_FETCH-LOGICAL-c540t-b115e4313c8b59a1b2690aa348483823bd203fd10d717b9a6f51f76d73459c3b3
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container_title Microsystems & nanoengineering
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creator Khalifa, Adam
Zaeimbashi, Mohsen
Zhou, Tony X.
Abrishami, Seyed Mahdi
Sun, Neville
Park, Seunghyun
Šumarac, Tamara
Qu, Jason
Zohar, Inbar
Yacoby, Amir
Cash, Sydney
Sun, Nian X.
description Electrical stimulation via invasive microelectrodes is commonly used to treat a wide range of neurological and psychiatric conditions. Despite its remarkable success, the stimulation performance is not sustainable since the electrodes become encapsulated by gliosis due to foreign body reactions. Magnetic stimulation overcomes these limitations by eliminating the need for a metal-electrode contact. Here, we demonstrate a novel microfabricated solenoid inductor (80 µm × 40 µm) with a magnetic core that can activate neuronal tissue. The characterization and proof-of-concept of the device raise the possibility that micromagnetic stimulation solenoids that are small enough to be implanted within the brain may prove to be an effective alternative to existing electrode-based stimulation devices for chronic neural interfacing applications.
doi_str_mv 10.1038/s41378-021-00320-8
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subjects 639/301/357/995
639/925/927/1007
Brain research
Electric contacts
Electrical stimuli
Electrodes
Engineering
Gliosis
Magnetic cores
Magnetic fields
Microelectrodes
Plating
Solenoids
Stimulation
title The development of microfabricated solenoids with magnetic cores for micromagnetic neural stimulation
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