Obesity paradox in patients with reduced ejection fraction eligible for device implantation – an observational study

Aims Patients with obesity have an overall higher cardiovascular risk, at the same time obesity could be associated with a better outcome in a certain subgroup of patients, a phenomenon known as the obesity paradox. Data are scarce in candidates for cardiac resynchronization therapy (CRT). We aimed...

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Bibliographic Details
Published in:ESC Heart Failure 2024-12, Vol.11 (6), p.3616-3625
Main Authors: Merkel, Eperke D., Behon, Anett, Masszi, Richard, Schwertner, Walter R., Kuthi, Luca, Veres, Boglárka, Osztheimer, István, Papp, Roland, Molnár, Levente, Zima, Endre, Gellér, László, Kosztin, Annamária, Merkely, Béla
Format: Article
Language:English
Subjects:
Aged
Body Mass Index
cardiac resynchronization therapy
Cardiac Resynchronization Therapy - methods
Diabetes
Ejection fraction
Female
Follow-Up Studies
Heart failure
Heart Failure - complications
Heart Failure - physiopathology
Heart Failure - therapy
Heart transplants
Humans
Hypertension
Ischemia
Male
Malnutrition
Medical history
Middle Aged
Mortality
Obesity
Obesity - complications
Obesity - physiopathology
Obesity Paradox
Observational studies
Original
Overweight
Patients
Retrospective Studies
Risk Factors
Statistical analysis
Stroke Volume - physiology
Survival Rate - trends
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Description
Summary:Aims Patients with obesity have an overall higher cardiovascular risk, at the same time obesity could be associated with a better outcome in a certain subgroup of patients, a phenomenon known as the obesity paradox. Data are scarce in candidates for cardiac resynchronization therapy (CRT). We aimed to investigate the association between body mass index (BMI) and all‐cause mortality in patients eligible for CRT. Methods Altogether 1,585 patients underwent cardiac resynchronization therapy between 2000–2020 and were categorized based on their BMI, 459 (29%) patients with normal weight (BMI 
ISSN:2055-5822
2055-5822
DOI:10.1002/ehf2.14961